Wei Ren
Peking Union Medical College
6 Papers
9 Citations
Wei Ren is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Chemistry & Pharmacokinetics. The author has an hindex of 5, co-authored 6 publications. Previous affiliations of Wei Ren include Capital Medical University.
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Papers
Pharmacokinetic-Pharmacodynamic Analysis on Inflammation Rat Model after Oral Administration of Huang Lian Jie Du Decoction
Wei Ren,Wei Ren,Ran Zuo,Yao-Nan Wang,Hongjie Wang,Jian Yang,Shao-Kun Xin,Shao-Kun Xin,Lingyu Han,Haiyu Zhao,Shu-Yan Han,Bo Gao,Hao Hu,Yuanjia Hu,Baolin Bian,Nan Si +15 more
TL;DR: It is demonstrated that HLJDD may restrain inflammation synergistically via its major constituents (alkaloids, flavonoids and iridoids) through its three-phase synchronous characterization of time-concentration-effect.
Metabolites profiling of 10 bufadienolides in human liver microsomes and their cytotoxicity variation in HepG2 cell
Lingyu Han,Hongjie Wang,Nan Si,Wei Ren,Bo Gao,Yan Li,Jian Yang,Miao Xu,Hai-Yu Zhao,Baolin Bian +9 more
TL;DR: The results showed that hydroxylation and dehydrogenation were the major metabolic pathways of bufadienolides in human liver microsomes (HLMs).
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Comparative Metabolism Study of Five Protoberberine Alkaloids in Liver Microsomes from Rat, Rhesus Monkey, and Human.
Yan Li,Yanyan Zhou,Nan Si,Lingyu Han,Wei Ren,Shao-Kun Xin,Shao-Kun Xin,Hongjie Wang,Ran Zuo,Ran Zuo,Xiaolu Wei,Jian Yang,Hai-Yu Zhao,Baolin Bian,Baolin Bian +14 more
TL;DR: The results demonstrated that the biotransformation characteristics of protoberberine alkaloids among different species had similarities as well differences that would be beneficial for us to better understand the pharmacological activities of protoberberines.
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Metabolic profiling of tenacigenin B, tenacissoside H and tenacissoside I using UHPLC‐ESI‐Orbitrap MS/MS
Can Zhao,Can Zhao,Lingyu Han,Wei Ren,Wei Ren,Hai-Yu Zhao,Shu-Yan Han,Shu-Yan Han,Wen-Xian Zheng,Wen-Xian Zheng,Li-Na Pang,Li-Na Pang,Xiao-Hong Li,Xiao-Hong Li,Ping-Ping Li,Ping-Ping Li +15 more
TL;DR: This is the first time that the metabolic profile of C-21 steroids from M. tenacissima has been explored in human liver microsomes, which is of great significance for subsequent pharmacokinetic and interaction research.
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