Wei Liu
Peking Union Medical College
35 Papers
82 Citations
Wei Liu is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Medicine & Neural stem cell. The author has an hindex of 12, co-authored 25 publications. Previous affiliations of Wei Liu include Capital Medical University & Tsinghua University.
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Papers
MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice
Wei Liu,Chang Liu,Jing-xi Zhu,Pengcheng Shu,Bin Yin,Yanhua Gong,Boqin Qiang,Jiangang Yuan,Xiaozhong Peng +8 more
TL;DR: It is demonstrated that APP is a target of miR-16 and the abnormally low expression of mi R-16 could potentially lead to APP protein accumulation in AD mice.
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The olfactory route is a potential way for SARS-CoV-2 to invade the central nervous system of rhesus monkeys.
Li Jiao,Yun Yang,Wenhai Yu,Yuan Zhao,Haiting Long,Jiahong Gao,Kaiyun Ding,Chunxia Ma,Jingmei Li,Siwen Zhao,Haixuan Wang,Haiyan Li,Mengli Yang,Jingwen Xu,Junbin Wang,Jing Yang,Dexuan Kuang,Fangyu Luo,Xingli Qian,Longjiang Xu,Bin Yin,Wei Liu,Hongqi Liu,Shuaiyao Lu,Xiaozhong Peng +24 more
TL;DR: In this paper, the authors explored the mechanisms of SARS-CoV-2 neurotropism via the established non-human primate model of COVID-19, and found that SARS infects neuro-derived SK-N-SH, glial-derived U251, and brain microvascular endothelial cells in vitro.
Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex.
Pengcheng Shu,Chao Wu,Xiangbin Ruan,Wei Liu,Lin Hou,Hongye Fu,Ming Wang,Chang Liu,Yi Zeng,Pan Chen,Bin Yin,Jiangang Yuan,Boqin Qiang,Xiaozhong Peng,Weimin Zhong +14 more
TL;DR: It is reported that microRNAs (miRNAs) are dispensable for stem-cell self-renewal and neuron production but essential for timing neocortical layer formation and specifying laminar fates.
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MicroRNA-129 modulates neuronal migration by targeting Fmr1 in the developing mouse cortex.
Chao Wu,Xiaoling Zhang,Pan Chen,Xiangbin Ruan,Wei Liu,Yanchao Li,Changjie Sun,Lin Hou,Bin Yin,Boqin Qiang,Pengcheng Shu,Xiaozhong Peng +11 more
TL;DR: The results suggest that miR-129-5p could modulate the expression of fragile X mental retardation 1 protein (FMRP) to ensure normal neuron positioning in the developing cerebral cortex.
The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling
Liang Li,Xiangbin Ruan,Chang Wen,Pan Chen,Wei Liu,Liyuan Zhu,Pan Xiang,Xiaoling Zhang,Qunfang Wei,Lin Hou,Bin Yin,Jiangang Yuan,Boqin Qiang,Pengcheng Shu,Xiaozhong Peng +14 more
TL;DR: It is shown that the COMPASS family histone methyltransferase co-factor ASH2L is required for maintaining neural progenitor cells (NPCs) and the production and positioning of projection neurons during neocortex development.
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