8 Papers
33 Citations
Wei Liu is an academic researcher from University of Science and Technology of China. The author has contributed to research in topics: Circular dichroism & Colloidal gold. The author has an hindex of 6, co-authored 8 publications. Previous affiliations of Wei Liu include City University of Hong Kong.
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Papers
Kinetics and mechanism of G-quadruplex formation and conformational switch in a G-quadruplex of PS2.M induced by Pb2+
TL;DR: Using circular dichroism and ultraviolet-visible spectroscopy, the spectral characteristics and the overall conformation of a G-quadruplex of PS2.M with an oligonucleotide sequence are determined andKinetic studies suggest that the Pb2+-induced folding of PS.M to G- quadruplex probably proceeds through a three-step pathway involving two intermediates.
Small organic molecules detection based on aptamer-modified gold nanoparticles-enhanced quartz crystal microbalance with dissipation biosensor.
TL;DR: An aptamer-based gold nanoparticles (AuNPs)-enhanced sensing strategy for detection of small molecules was developed and the resulting aptasensor exhibited several excellent characteristics such as high sensitivity, selectivity, good stability, and reproducibility.
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A simple colorimetric pH alarm constructed from DNA–gold nanoparticles
TL;DR: Single-stranded homopolymeric deoxyadenosines (abbreviated as poly (dA)) as recognition elements and gold nanoparticles as reporter parts for the construction of pH alarms, which are able to produce sharp colorimetric responses upon specific pH thresholds within the range from pH 2 to 4.
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The unfolding of G-quadruplexes and its adverse effect on DNA-gold nanoparticles-based sensing system.
Sheng Cheng,Bin Zheng,Bin Zheng,Mozhen Wang,Xuewu Ge,Qing Zhao,Wei Liu,Wei Liu,Michael H.W. Lam +8 more
TL;DR: The interaction between G-quadruplexes and AuNP demonstrated that long time incubation between DNAs and AuNPs would possibly make it unable to distinguish G- quadruplex from ssDNA, and an biosensing system consisting of PW17 and Au NPs was developed to detect Pb(2+).
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G-quadruplex formation and sequence effect on the assembly of G-rich oligonucleotides induced by Pb2+ ions
Wei Liu,Wei Liu,Bin Zheng,Bin Zheng,Sheng Cheng,Sheng Cheng,Yan Fu,Wei Li,Tai-Chu Lau,Haojun Liang +9 more
TL;DR: The studies show that the connecting loops of the DNA play an important role in modulating the structures and are consistent with the higher stability of T2 that contains four G-quartets, as opposed to HTG and TBA that have only three and two quartets, respectively.
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