Wei Li

TL;DR: In this paper, the effect of polymer additives on the "exact coherent states" (ECS), in the plane Poiseuille geometry, was studied and several key aspects of the turbulent drag reduction phenomenon were found, including: delay in transition to turbulence; drag reduction onset threshold; diameter and concentration effects.

TL;DR: These studies show that VEGF and PlGF regulate transcription of KCC3b and KCC4 in erythroid cells via activation of HIF‐1α, independent of hypoxia, which provides novel therapeutic targets for regulation of cell volume in RBC precursors, and thus, amelioration of dehydration in R BCs in sickle cell disease.

TL;DR: A simple "do-it-yourself" perfusable vasculature model that incorporates a confluent endothelial cell monolayer along the channel lumen and recapitulates complex vascular geometries such as curvature is developed that can be cultured with human aortic endothelial cells (HAECs).

TL;DR: It is hypothesized that purely physical interactions - akin to "scratches" or collisions - between endothelial cells and stiff SCD RBCs breaking through the cell-free layer are sufficient to cause endothelial inflammation in the absence of adhesion or vaso-occlusion.