Wei Li
Indiana University
40 Papers
183 Citations
Wei Li is an academic researcher from Indiana University. The author has contributed to research in topics: Haemophilus ducreyi & Medicine. The author has an hindex of 14, co-authored 35 publications. Previous affiliations of Wei Li include Indiana University – Purdue University Indianapolis & University of Virginia.
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Papers
ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease
Jilu Zhang,Abdulraouf Ramadan,Brad Griesenauer,Wei Li,Matthew J. Turner,Chen Liu,Reuben Kapur,Helmut Hanenberg,Bruce R. Blazar,Isao Tawara,Sophie Paczesny +10 more
TL;DR: The findings suggest that ST2 is a therapeutic target for severe GVHD and that the ST2/IL-33 pathway could be investigated in other T cell–mediated immune disorders with loss of tolerance.
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An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition
Edouard Forcade,Katelyn Paz,Ryan Flynn,Brad Griesenauer,Tohti Amet,Wei Li,Liangyi Liu,Giorgos Bakoyannis,Di Jiang,Hong Wei Chu,Mercedes Lobera,Jianfei Yang,David S. Wilkes,Jing Du,Kate H. Gartlan,Geoffrey R. Hill,Kelli P. A. MacDonald,Eduardo Espada,Patrick Blanco,Jonathan S. Serody,John Koreth,Corey Cutler,Joseph H. Antin,Robert J. Soiffer,Jerome Ritz,Sophie Paczesny,Bruce R. Blazar +26 more
TL;DR: The data suggest CD146-expressing T cells as a cGvHD biomarker and suggest that targeting the Th17 pathway may represent a promising therapy for cGVHD.
MMPs/TIMPs imbalances in the peripheral blood and cerebrospinal fluid are associated with the pathogenesis of HIV-1-associated neurocognitive disorders
Yanyan Xing,Nicole Shepherd,Jie Lan,Wei Li,Sushmita Rane,Samir K. Gupta,Shanxiang Zhang,Jun Dong,Qigui Yu +8 more
TL;DR: Plasma from HIV-1 patients directly induced integrity disruption of an in vitro blood-brain barrier (BBB) model, leading to increased BBB permeability and robust transmigration of monocytes/macrophages.
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Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease
Wei Li,Liangyi Liu,Aurelie Gomez,Jilu Zhang,Abdulraouf Ramadan,Qing Zhang,Sung Won Choi,Peng Zhang,Joel K. Greenson,Chen Liu,Di Jiang,Elizabeth L. Virts,Stephanie L. Kelich,Hong Wei Chu,Ryan Flynn,Bruce R. Blazar,Helmut Hanenberg,Samir M. Hanash,Sophie Paczesny +18 more
TL;DR: Through in-depth, large-scale proteomic profiling of presymptomatic samples, a T cell population expressing both CD146, a cell adhesion molecule, and CCR5, a chemokine receptor that is upregulated as early as 14 days after transplantation in patients who develop GI-GVHD is identified.