24 Papers
38 Citations
Wanxin Li is an academic researcher from Fujian Agriculture and Forestry University. The author has contributed to research in topics: Aeromonas hydrophila & Biology. The author has an hindex of 12, co-authored 19 publications. Previous affiliations of Wanxin Li include Guangdong Ocean University.
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Papers
Alanine Enhances Aminoglycosides-Induced ROS Production as Revealed by Proteomic Analysis.
TL;DR: The results suggest a novel mechanism by which alanine facilitates kanamycin killing of antibiotic-resistant bacteria via promoting ROS production.
Identification and efficacy of glycine, serine and threonine metabolism in potentiating kanamycin-mediated killing of Edwardsiella piscicida.
TL;DR: The results shed light on the mechanism of how glucose promoting the amino acids biosynthesis and metabolism to potentiate kanamycin to kill antibiotic-resistant bacteria and suggested that adjusting amino acid biosynthesisand metabolism might be a strategy to become phenotypic resistance to antibiotics in bacteria.
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Integrated Succinylome and Metabolome Profiling Reveals Crucial Role of S-Ribosylhomocysteine Lyase in Quorum Sensing and Metabolism of Aeromonas hydrophila.
Zujie Yao,Zujie Yao,Zhuang Guo,Yuqian Wang,Wanxin Li,Yuying Fu,Yuexu Lin,Wenxiong Lin,Xiangmin Lin +8 more
TL;DR: The succinylation of lysines on S-ribosylhomocysteine lyase (LuxS) at the K23 and K30 sites positively regulate the production of the quorum sensing autoinducer AI-2, and that these PTMs ultimately alter its competitiveness with another pathogen, Vibrio alginolyticus.
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Systematically integrated metabonomic-proteomic studies of Escherichia coli under ciprofloxacin stress.
TL;DR: The metabolite and protein profiles under CFLX stress are identified, indicating the mode of action of antibiotics in E. coli and the decreasing metabolic activity inE.
45
Proteomic Analysis Reveals That Metabolic Flows Affect the Susceptibility of Aeromonas hydrophila to Antibiotics.
TL;DR: Investigation of the adaptive resistance mechanism in A. hydrophila by multiple proteomic methods suggests that a compound comprising exogenous metabolites in combination with various antibiotics could have a significant bactericidal effect and might come into widespread use, especially together with tetracycline antibiotics.