Wangyang Hu
Zhejiang University
4 Papers
Wangyang Hu is an academic researcher from Zhejiang University. The author has contributed to research in topics: Inflammation & Lactoferrin. The author has an hindex of 3, co-authored 4 publications.
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Papers
Cathelicidin-WA Improves Intestinal Epithelial Barrier Function and Enhances Host Defense against Enterohemorrhagic Escherichia coli O157:H7 Infection
TL;DR: CWA attenuated EHEC-induced inflammation, intestinal epithelial barrier damage, and microbiota disruption in the intestine of mice, suggesting that CWA may be an effective therapy for many intestinal diseases.
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Porcine lactoferrin-derived peptide LFP-20 protects intestinal barrier by maintaining tight junction complex and modulating inflammatory response.
TL;DR: L FP-20 prevents the inflammatory response and disruption of tight junction structure induced by LPS, suggesting the potential use of LFP-20 as a prophylactic agent to protect intestinal barrier function.
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LFP-20, a porcine lactoferrin peptide, ameliorates LPS-induced inflammation via the MyD88/NF-κB and MyD88/MAPK signaling pathways.
TL;DR: Investigating its anti-inflammatory effects in lipopolysaccharide-stimulated pig alveolar macrophages in vitro and systemic inflammation in an in vivo mouse model indicated that LFP-20 prevents the LPS-induced inflammatory response by inhibiting MyD88/NF-κB and MyD 88/MAPK signaling pathways, and sheds light on the potential use of L FP-20 in the therapy of L PS-mediated sepsis.
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Antibacterial, Cytotoxicity and Mechanism of the Antimicrobial Peptide KR-32 in Weaning Piglets
TL;DR: Research reveals AMP KR-32 may have potential application for the control of infectious disease in livestock, and furthermore, AMPKR-32 is a potent antibacterial agent.
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