Wang Yang
Fudan University
18 Papers
16 Citations
Wang Yang is an academic researcher from Fudan University. The author has contributed to research in topics: Prostate cancer & LNCaP. The author has an hindex of 4, co-authored 18 publications.
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Papers
USP16 regulates castration-resistant prostate cancer cell proliferation by deubiquitinating and stablizing c-Myc.
Jianchao Ge,Wandong Yu,Junhong Li,Hangbin Ma,Pengyu Wang,Yinghao Zhou,Wang Yang,Jun Zhang,Guowei Shi +8 more
TL;DR: In this paper, a mouse xenograft model of PC3 cells was established to confirm the function of USP16 in vitro and in vivo, and the deubiquitinase was shown to significantly suppress the growth of PCa cells both in vivo and in vitro.
17-DMCHAG, a new geldanamycin derivative, inhibits prostate cancer cells through Hsp90 inhibition and survivin downregulation
Jifeng Wang,Zhenyu Li,Zhiyuan Lin,Baobing Zhao,Wang Yang,Ruixian Peng,Meifang Wang,Chunhua Lu,Guowei Shi,Yuemao Shen +9 more
TL;DR: 17-DMCHAG is a highly effective and low-hepatotoxic geldanamycin derivative that exhibits antitumor activity against human prostate cancer cells and is a potential treatment for prostate cancer.
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Low expression of microRNA‑30c promotes prostate cancer cells invasion involved in downregulation of KRAS protein
Jun Zhang,Wang Xilong,Wang Yangyun,Ruixian Peng,Zhiyuan Lin,Wang Yang,Bo Hu,Jifeng Wang,Guowei Shi +8 more
TL;DR: It is demonstrated that overexpression of miR-30c inhibits prostate cancer cell line proliferation, migration and invasion, which was possibly caused by downregulation of KRAS protein by miR -30c.
•Journal Article
The HSP90 inhibitor 17-PAG effectively inhibits the proliferation and migration of androgen-independent prostate cancer cells.
Ruixian Peng,Zhenyu Li,Zhiyuan Lin,Wang Yang,Wei Wang,Bo Hu,Wang Xilong,Zhang Jun,Wang Yangyun,Renyuan Zhou,Chunhua Lu,Yuemao Shen,Jifeng Wang,Guowei Shi +13 more
TL;DR: A new GA derivative, 17-PAG (17-(propynylamino)-17-demethoxygeldanamycin), which demonstrates highly effective anti-tumor activity against androgen-independent prostate cancer cells is reported.
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The Correlation between Severity of Overactive Bladder Symptoms with Female Sexual Dysfunction and Sexual Satisfaction of Partners.
TL;DR: Severe OAB was closely associated with female sexual dysfunction and sexual satisfaction of partners, and the urgency and urge incontinence should be focused for OAB management.
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