Wang Shifa
Nanjing Forestry University
11 Papers
12 Citations
Wang Shifa is an academic researcher from Nanjing Forestry University. The author has contributed to research in topics: Benzimidazole & Ursolic acid. The author has an hindex of 5, co-authored 11 publications.
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Papers
Synthesis, in vitro antimicrobial and cytotoxic activities of new carbazole derivatives of ursolic acid
TL;DR: A series of new carbazole derivatives of ursolic acid were designed and synthesized in an attempt to develop potent antimicrobial or antitumor agents, and compound 5e was found to be the most potent compound with IC50 values comparable to those of doxorubicin.
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Synthesis and biological evaluation of novel N-substituted 1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid as potential antimicrobial agents.
TL;DR: A series of new N-substituted 1H-dibenzo[a,c]carbazole derivatives synthesized from dehydroabietic acid displayed pronounced antimicrobial activity against tested strains with low MIC values and exhibited potent inhibitory activity comparable to reference drugs amikacin and ketoconazole.
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Synthesis and in vitro cytotoxic evaluation of new 1H-benzo[d]imidazole derivatives of dehydroabietic acid.
TL;DR: A series of new 1H-benzo[d]imidazole derivatives of dehydroabietic acid were designed and synthesized as potent antitumor agents and showed significant cytotoxic activities against two hepatocarcinoma cells and reduced cytotoxicity against noncancerous human hepatocyte (LO2).
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Synthesis and Evaluation of New Quinoxaline Derivatives of Dehydroabietic Acid as Potential Antitumor Agents.
Wen Gu,Wang Shuang,Xiao-Yan Jin,Ya-Liang Zhang,Dawei Hua,Ting-Ting Miao,Xu-Bing Tao,Wang Shifa +7 more
TL;DR: A series of new quinoxaline derivatives of dehydroabietic acid (DAA) were designed and synthesized as potential antitumor agents and confirmed that compound 4b could induce the apoptosis of SMMC-7721 cells in a dose-dependent manner.
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Patent
Dehydroabietic acid benzimidazole derivatives with antitumor activity as well as preparation method and application of dehydroabietic acid benzimidazole derivatives
Gu Wen,Xu-Bing Tao,Ting-Ting Miao,Xiao-Yan Jin,Hao Chen,Geng Yi,Wang Shifa +6 more
- 22 Dec 2017
TL;DR: In this article, the authors have shown that Nitrogen-containing heterocyclic compounds are pharmaceutically acceptable salt of the dehydroabietic acid benzimidazole derivatives and have good antitumor bioactivity.
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