Objectives:To explore whether combined therapy with donepezil and acupuncture is better than treatment with donepezil or acupuncture individually in a rat model of Alzheimer’s disease.Methods:In th...

https://journals.sagepub.com/doi/pdf/10.1136/acupmed-2016-011310

Effects of manual acupuncture combined with donepezil in a mouse model of Alzheimer's disease.

Aging involves cognitive decline and prominent alterations in brain activity. Electroacupuncture (EA), a traditional Chinese medicine approach, is demonstrated to be effective in improving cognitive function of older adults. However, the specific neural mechanism underlying this modulation effect remains unclear. In this study, we used functional magnetic resonance imaging (fMRI) to investigate whether EA could improve cognitive performance of community-dwelling older adults and whether these potential improvements are associated with the EA-induced brain functional connectivity alterations. Thirty healthy older adults were recruited and randomly assigned to the EA group and the control group. Behaviorally, we observed an EA-induced improvement in cognitive performance of older adults in the Montreal Cognitive Assessment. On a neural perspective, the EA intervention significantly increased the functional connectivity within the default mode network. Moreover, we found a positive association between the improvement in delayed memory performance and the alterations in the ventral medial prefrontal cortex-hippocampal formation connectivity in the EA group. This study extends previous findings by showing that healthy older adults exhibit neural plasticity manifested as increased functional connectivity after EA sessions, which could induce therapeutic effects in the treatment of neurodegenerative diseases.

Electroacupuncture Modulates Resting-State Functional Connectivity in the Default Mode Network for Healthy Older Adults

Acupuncture for radiotherapy-induced nausea and vomiting: A systematic review protocol.

Ad dress for Cor res pon den ce/Ya z›fl ma Ad re si: Hale Zeynep Batur Çağlayan MD, Gazi University Faculty of Medicine, Department of Neurology, Ankara, Turkey Phone: +90 505 527 66 14 E-mail: halezeynep@gazi.edu.tr ORCID ID: orcid.org/0000-0002-3279-1842 Re cei ved/Ge lifl Ta ri hi: 30.05.2017 Ac cep ted/Ka bul Ta ri hi: 31.07.2017 This review was prepared by members of the Turkish Neurological Society Working Group of Young Neurologists upon the recommendation of the Board of Directors of the Turkish Neurological Association and published with the approval of the Board of Directors. ©Copyright 2018 by Turkish Neurological Society Turkish Journal of Neurology published by Galenos Publishing House. Traditional, complementary, and alternative medicine practices are used in the prevention, diagnosis, and treatment of a wide variety of diseases in the world. Such practices in Turkey are regulated by the “Regulation of Traditional and Complementary Medicine Practice” issued by the Ministry of Health in the Official Gazette of the Republic of Turkey (Issue: 29158, 27th October 2014). The appendix of this regulation defines 15 practices that can be applied in units and practice centers. These applications include; 1. Acupuncture, 2. Apitherapy, 3. Phytotherapy, 4. Hypnosis, 5. Leech therapy (Hirudotherapy), 6. Homeopathy, 7. Chiropractic, 8. Cupping, 9. Maggot therapy, 10. Mesotherapy, 11. Prolotherapy, 12. Osteopathy, 13. Ozone therapy, 14. Reflexology, and 15. Music therapy. In this review, the indications of these 15 applications in the field of neurology are examined and current opinions of the evidence-based medical data are summarized.

The Assessment of Efficiency of Traditional and Complementary Medicine Practices in Neurology

Plum-blossom needle for coronavirus disease 2019-related headache: A protocol for systematic review and meta-analysis.

Introduction The aim of this protocol is to provide the methods used to assess the effectiveness and safety of acupuncture for the treatment of patients with Alzheimer9s disease. Methods and analysis We will search the following electronic databases: The Cochrane Library, PubMed, Medline, Embase, PsycINFO, Chinese Biomedical Literature Database, Chinese Medical Current Contents and China National Knowledge Infrastructure without restriction of language and publication status. Other sources such as Chinese acupuncture journals and the reference list of selected studies will also be searched. After screening the studies, a meta-analysis of randomised controlled trials will be conducted, if possible. Results expressed as risk ratios for dichotomous data and standardised or weighted mean differences for continuous data, will be used for data synthesis. Dissemination The protocol of this systematic review will be disseminated in a peer-reviewed journal and presented at a relevant conference. Trial registration number PROSPERO CRD42014009619

https://bmjopen.bmj.com/content/bmjopen/4/8/e005896.full.pdf

Acupuncture for patients with Alzheimer's disease: a systematic review protocol

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Acupuncture for patients with Alzheimer's disease: a systematic review protocol