Wang He
Sun Yat-sen University
41 Papers
134 Citations
Wang He is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Bladder cancer & Medicine. The author has an hindex of 17, co-authored 27 publications. Previous affiliations of Wang He include Memorial Hospital of South Bend.
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Papers
LNMAT1 promotes lymphatic metastasis of bladder cancer via CCL2 dependent macrophage recruitment.
Changhao Chen,Wang He,Jian Huang,Bo Wang,Hui Li,Qingqing Cai,Feng Su,Junming Bi,Hongwei Liu,Bin Zhang,Ning Jiang,Guangzheng Zhong,Yue Zhao,Wen Dong,Tianxin Lin +14 more
TL;DR: It is demonstrated that a long noncoding RNA LNMAT1 promotes LN metastasis of bladder cancer via recruitment of TAMs through epigenetic regulation of CCL2 expression, which provides a plausible mechanism for L NMAT1-modulated tumor microenvironment in lymphatic metastasis.
Long Noncoding RNA LBCS Inhibits Self-Renewal and Chemoresistance of Bladder Cancer Stem Cells through Epigenetic Silencing of SOX2.
Xu Chen,Ruihui Xie,Peng Gu,Ming Huang,Jinli Han,Wen Dong,Weibin Xie,Bo Wang,Wang He,Guangzheng Zhong,Ziyue Chen,Jian Huang,Tianxin Lin +12 more
TL;DR: As a novel regulator, lnc-LBCS plays an important tumor-suppressor role in BCSCs’ self-renewal and chemoresistance, contributing to weak tumorigenesis and enhanced chemosensitivity and may represent a therapeutic target for clinical intervention in chemoresistant bladder cancer.
CD103+ Tumor Infiltrating Lymphocytes Predict a Favorable Prognosis in Urothelial Cell Carcinoma of the Bladder
Bo Wang,Shaoxu Wu,Hong Zeng,Zhuowei Liu,Wen Dong,Wang He,Xu Chen,Xiaoliang Dong,Limin Zheng,Tianxin Lin,Jian Huang +10 more
TL;DR: It is suggested that CD8(+) T cells might have a significant role in tumor immunity by expressing CD103 in intratumor regions of bladder urothelial cell carcinoma tissues, and could represent a favorable prognostic predictor of overall and recurrence-free survival.
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SUMOylation promotes extracellular vesicle–mediated transmission of lncRNA ELNAT1 and lymph node metastasis in bladder cancer
Changhao Chen,Hanhao Zheng,Yuming Luo,Yao Kong,Mingjie An,Yuting Li,Wang He,Bowen Gao,Yue Zhao,Hao Huang,Jian Huang,Tianxin Lin +11 more
TL;DR: In this paper, the authors show that a cell-secreted EV mediated intercellular communication with human lymphatic endothelial cells (HLECs) through transmission of the long noncoding RNA ELNAT1 and promoted lymphangiogenesis and lymph node metastasis in a SUMOylation-dependent manner in both cultured BCa cell lines and mouse models.
Programmed death ligand‐1 is associated with tumor infiltrating lymphocytes and poorer survival in urothelial cell carcinoma of the bladder
Bo Wang,Wenwei Pan,Meihua Yang,Wenjuan Yang,Wang He,Xu Chen,Junming Bi,Ning Jiang,Jian Huang,Tianxin Lin +9 more
TL;DR: Results suggested that an exhausted immune state occurred in the tumor stroma in UCB and further clinical development of immune‐checkpoint inhibitors may be effective for resectable patients with UCB.
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