W. Jy
University of Miami
10 Papers
56 Citations
W. Jy is an academic researcher from University of Miami. The author has contributed to research in topics: Endothelial stem cell & Bone marrow suppression. The author has an hindex of 8, co-authored 10 publications.
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Papers
•Journal Article
Clinical significance of platelet microparticles in autoimmune thrombocytopenias
TL;DR: It is concluded that PMPs play an important role in hemostasis in patients withThrombocytopenia, and that high concentrations of hemostatically active PMP can be thrombogenic in certain clinical settings.
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Microparticle-mediated thrombin generation assay: increased activity in patients with recurrent thrombosis.
Loreta Bidot,W. Jy,Carlos Bidot,J. J. Jimenez,V. Fontana,Lawrence L. Horstman,Yeon-Soong Ahn +6 more
TL;DR: In this paper, the authors developed MP-mediated thrombin generation assay (TGA) and measured a series of patients with thrombosis (TBS) and normal controls (NC).
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Phenotypic assessment of endothelial microparticles in patients with heart failure and after heart transplantation: Switch from cell activation to apoptosis
Santiago Garcia,Julio A. Chirinos,Javier León Jiménez,Freddy del Carpio Munoz,Mariana Canoniero,W. Jy,Joaquin J. Jimenez,Lawrence L. Horstman,Yeon S. Ahn +8 more
TL;DR: Cardiac transplantation is associated with a different pattern of endothelial cell injury than that seen in heart failure, and the phenotypic assessment of EMPs in post-transplant patients is consistent with increased apoptotic activity.
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More on: cellular microparticles: what are they bad or good for?
TL;DR: Freyssinet et al. as mentioned in this paper showed that a necessary prelude to vesiculation and shedding of microparticles (MP) is migration of phosphatidylserine (PS) from the inner to the outer leaflet of the membrane bilayer.
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Complement in neurobiology.
Lawrence L. Horstman,W. Jy,Yeon S. Ahn,Amir-Hadi Maghzi,Masoud Etemadifar,Jonathan Steven Alexander,Jeanie McGee,Alireza Minagar +7 more
TL;DR: Cutting-edge work on the role of C-mediated natural antibodies in autoimmunity and treatment strategies based on those findings are summarized, e.g., for remyelination and post-ischemic stroke repair.
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