W.E. Kempf
Technische Universität München
7 Papers
1 Citations
W.E. Kempf is an academic researcher from Technische Universität München. The author has contributed to research in topics: Chemokine & Chemokine receptor. The author has an hindex of 3, co-authored 7 publications.
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Papers
Long Noncoding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization
Francesca Fasolo,Hong Jin,Greg Winski,Ekaterina Chernogubova,Jessica Pauli,Hanna Winter,Daniel Y. Li,Nadiya Glukha,Sabine Bauer,Susanne Metschl,Zhiyuan Wu,Marlys L. Koschinsky,Muredach P. Reilly,Jaroslav Pelisek,W.E. Kempf,Hans-Henning Eckstein,Oliver Soehnlein,Oliver Soehnlein,Ljubica Perisic Matic,Ulf Hedin,Alexandra Bäcklund,Claes Bergmark,Valentina Paloschi,Lars Maegdefessel,Lars Maegdefessel +24 more
TL;DR: In this paper, the authors assessed the functional properties of long noncoding RNAs (lncRNAs) and found that they are important regulators of biological processes involved in vascular tissue homeostasis and disease development.
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Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis
Julia Hinterdobler,Simin Schott,Hong Jin,Almut Meesmann,Anna-Lena Steinsiek,Anna-Sophia Zimmermann,Jana Wobst,Philipp Müller,Carina Mauersberger,Baiba Vilne,Alexandra Baecklund,Chien-Sin Chen,Aldo Moggio,Quinte Braster,Michael Molitor,Markus Krane,W.E. Kempf,Karl-Heinz Ladwig,Michael Hristov,Maarten Hulsmans,Ingo Hilgendorf,Christian Weber,Philip Wenzel,Christoph Scheiermann,Christoph Scheiermann,Lars Maegdefessel,Lars Maegdefessel,Oliver Soehnlein,Peter Libby,Matthias Nahrendorf,Heribert Schunkert,Thorsten Kessler,Hendrik B. Sager +32 more
TL;DR: This paper showed that acute mental stress significantly contributes to the initiation and progression of human disease, including cardiovascular conditions, including heart, lung, skin, and, if present, atherosclerotic plaques.
Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting
Christos Kontos,Omar El Bounkari,Christine Krammer,Dzmitry Sinitski,Kathleen Hille,Chunfang Zan,Guangyao Yan,Sijia Wang,Ying Gao,Markus Brandhofer,Remco T. A. Megens,Adrian Hoffmann,Jessica Pauli,Yaw Asare,Simona Gerra,Priscila Bourilhon,Lin Leng,Hans-Henning Eckstein,W.E. Kempf,Jaroslav Pelisek,Jaroslav Pelisek,Ozgun Gokce,Lars Maegdefessel,Richard Bucala,Martin Dichgans,Christian Weber,Aphrodite Kapurniotu,Juergen Bernhagen +27 more
TL;DR: An engineered GPCR-ectodomain-based mimicry principle is established that differentiates between disease-exacerbating and -protective pathways and chemokine-selectively interferes with atherosclerosis.
Targeting tumor-resident mast cells for effective anti-melanoma immune responses
Susanne Kaesler,Florian Wölbing,Florian Wölbing,W.E. Kempf,Yuliya Skabytska,Yuliya Skabytska,Martin Köberle,Thomas Volz,Tobias Sinnberg,Teresa Amaral,Sigrid M. C. Möckel,Amir S. Yazdi,Gisela Metzler,Martin Schaller,Karin Hartmann,Benjamin Weide,Claus Garbe,Hans-Georg Rammensee,Martin Röcken,Tilo Biedermann,Tilo Biedermann +20 more
TL;DR: Findings provide conclusive evidence for a "Trojan horse treatment strategy" in which the plasticity of cancer-resident immune cells, such as MCs, is used as a target to boost tumor immune defense.