Viviana Gradinaru

TL;DR: In this paper, the authors present methods for the treatment of bladder dysfunction, including detrusor hyperreflexia and external sphincter dyssynergia, fecal incontinence, and/or sexual dysfunction in an individual via the use of stably expressed light-responsive opsin proteins capable of selective hyperpolarization or depolarization of the neural cells that innervate the muscles responsible for physiologic functioning of the urinary bladder, external urethra, and the male and female genitalia.

TL;DR: In this article, peptide sequences capable of directing the delivery of adeno-associated viruses (AAV) for targeting them to certain environments, e.g. the nervous system and heart, in the subject's body.

TL;DR: In this article, a procedure for the generation of a molecule de canal ionique activee par la lumiere dans une cellule and the activation of a ladite molecule de canaux ionique en reaction au stimulus lumineux is described.

TL;DR: The authors concerne des polynucleotides and des procedes d'expression de proteines activees par la lumiere dans des cellules animales and d'alteration d'un potentiel d'action des cellule par une stimulation optique.