Vivek Srinivas
Stockholm University
17 Papers
18 Citations
Vivek Srinivas is an academic researcher from Stockholm University. The author has contributed to research in topics: Chemistry & Ribonucleotide reductase. The author has an hindex of 7, co-authored 11 publications.
Chat about Author
Papers
Drop-on-demand sample delivery for studying biocatalysts in action at X-ray free-electron lasers
Franklin D. Fuller,Sheraz Gul,Ruchira Chatterjee,E. Sethe Burgie,Iris D. Young,Hugo Lebrette,Vivek Srinivas,Aaron S. Brewster,Tara Michels-Clark,Jonathan A. Clinger,Babak Andi,Mohamed Ibrahim,Ernest Pastor,Casper de Lichtenberg,Rana Hussein,Christopher J. Pollock,Miao Zhang,Claudiu A. Stan,Thomas Kroll,Thomas Fransson,Clemens Weninger,Markus Kubin,Pierre Aller,Louise Lassalle,Philipp Bräuer,Mitchell D. Miller,Muhamed Amin,Muhamed Amin,Sergey Koroidov,Sergey Koroidov,Christian G. Roessler,Christian G. Roessler,Marc Allaire,Raymond G. Sierra,P. T. Docker,James M. Glownia,Silke Nelson,Jason E. Koglin,Diling Zhu,Matthieu Chollet,Sanghoon Song,Henrik T. Lemke,Henrik T. Lemke,Mengning Liang,Dimosthenis Sokaras,Roberto Alonso-Mori,Athina Zouni,Johannes Messinger,Johannes Messinger,Uwe Bergmann,Amie K. Boal,J. Martin Bollinger,Carsten Krebs,Martin Högbom,Martin Högbom,George N. Phillips,Richard D. Vierstra,Nicholas K. Sauter,Allen M. Orville,Jan Kern,Jan Kern,Vittal K. Yachandra,Junko Yano +62 more
TL;DR: A robust way of delivering controlled sample amounts on demand using acoustic droplet ejection coupled with a conveyor belt drive that is optimized for crystallography and spectroscopy measurements of photochemical and chemical reactions over a wide range of time scales is presented.
A Rare Lysozyme Crystal Form Solved Using Highly Redundant Multiple Electron Diffraction Datasets from Micron-Sized Crystals
Hongyi Xu,Hugo Lebrette,Taimin Yang,Vivek Srinivas,Sven Hovmöller,Martin Högbom,Xiaodong Zou +6 more
TL;DR: It is shown that merging data from 33 crystals significantly improves not only the data completeness, overall I/σ and the data redundancy, but also the quality of the final atomic model, extremely useful for electron beam-sensitive crystals of low symmetry or with a preferred orientation on the TEM grid.
68
High-Resolution XFEL Structure of the Soluble Methane Monooxygenase Hydroxylase Complex with its Regulatory Component at Ambient Temperature in Two Oxidation States.
Vivek Srinivas,Rahul Banerjee,Hugo Lebrette,Jason C. Jones,Oskar Aurelius,In-Sik Kim,Cindy C. Pham,Sheraz Gul,Kyle D. Sutherlin,Asmit Bhowmick,Juliane John,Esra Bozkurt,Thomas Fransson,Pierre Aller,A. Butryn,Isabel Bogacz,Philipp S. Simon,Stephen Keable,Alexander Britz,Kensuke Tono,Kyung Sook Kim,Sang-Youn Park,Sang Jae Lee,Jae Hyun Park,Roberto Alonso-Mori,Franklin D. Fuller,Alexander Batyuk,Aaron S. Brewster,Uwe Bergmann,Nicholas K. Sauter,Allen M. Orville,Vittal K. Yachandra,Junko Yano,John D. Lipscomb,Jan Kern,Martin Högbom +35 more
TL;DR: Microcrystals of the sMMOH:MMOB complex from Methylosinus trichosporium OB3b were serially exposed to XFEL pulses, providing new insight into the manner by which the diiron cluster and the active site environment are reorganized by the regulatory protein component in order to enhance the steps of oxygen activation and methane oxidation.
Assembly of nonheme Mn/Fe active sites in heterodinuclear metalloproteins
TL;DR: The current understanding of the assembly of the heterodinuclear cofactor in the two different protein groups in which it has been identified, ribonucleotide reductase R2c proteins and R2-like ligand-binding oxidases is reviewed.
Divergent assembly mechanisms of the manganese/iron cofactors in R2lox and R2c proteins.
Yuri Kutin,Vivek Srinivas,Matthieu Fritz,Ramona Kositzki,Hannah S. Shafaat,James A. Birrell,Eckhard Bill,Michael Haumann,Wolfgang Lubitz,Martin Högbom,Martin Högbom,Julia J. Griese,Nicholas Cox,Nicholas Cox +13 more
TL;DR: The divergent metal loading mechanisms are correlated with the putative in vivo functions of R2c and R2lox, and most likely with the intracellular MnII/FeII concentrations in the host organisms from which they were isolated.
25