Virgínia Oliveira Crema
University of São Paulo
14 Papers
83 Citations
Virgínia Oliveira Crema is an academic researcher from University of São Paulo. The author has contributed to research in topics: RHOA & RAC1. The author has an hindex of 5, co-authored 14 publications.
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Papers
Tyrosine kinase inhibitor TKI-258 inhibits cell motility in oral squamous cell carcinoma in vitro.
Anna Cecília Dias Maciel Carneiro,Isadora Caixeta da Silveira,Arthur Silva Rezende,Bruna Raphaela Oliveira Silva,Virgínia Oliveira Crema +4 more
TL;DR: The results suggest that the tyrosine kinase inhibitor TKI-258 has an inhibitory effect on cell motility, affecting F-actin, cell migration, and cell invasion, and probably, these processes are regulated by signaling pathways FGFRs and/or PDGFRsand/or VEGFRs.
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RhoA/ROCKs signaling is increased by treatment with TKI-258 and leads to increased apoptosis in SCC-4 oral squamous cell carcinoma cell line.
Anna Cecília Dias Maciel Carneiro,Fernanda Bernadelli De Vito,Helio Moraes-Souza,Virgínia Oliveira Crema +3 more
TL;DR: TKI-258 stimulates apoptosis in SCC-4 cells of oral squamous cell carcinoma and possibly, RhoA GTPase and their effectors ROCKs participate in the signalling pathway inhibited by TKI- 258.
3
Comparison of the use of Solidago chilensis (Arnica) and low-level laser therapy for the prevention of oral mucositis in patients submitted of head and neck radiotherapy and/or high toxicity chemotherapy
Ana Cristina Lopes,Giovana Ferreira Gonçalves,Anna Cecília Dias Maciel Carneiro,André Luiz Pantoja dos Santos,Frederico Nobrega Tomas,Leonardo José Rodrigues de Oliveira,Karina Ferrazzoli Devienne,Virgínia Oliveira Crema +7 more
TL;DR: In this paper, the authors evaluated the uses of Solidago chilensis (Arnica) for oral mucositis prevention in patients submitted to radiotherapy for head and neck tumors treatment and/or high toxicity chemotherapy.
1
Anti-Proliferative Role of the Tyrosine Kinase Inhibitors TKI-258 on Oral Squamous Cell Carcinoma In Vitro.
Isadora Caixeta da Silveira,Anna Cecília Dias Maciel Carneiro,Lorraine Stephanie Hiss,Virgínia Oliveira Crema +3 more
TL;DR: TKI-258 treatment leads to an important reduction in proliferation rate in SCC-4 cells by in a concentration dependent manner and is a promising option for novel therapeutics for OSCC, especially if associated with PI3K inhibition.
1
Effects of tobacco smoke inhalation on the morphology and cell proliferation rate in Wistar rats submandibular glands
Lorraine Stephanie Hiss,Anna Cecília Dias Maciel Carneiro,Rodrigo César Rosa,Adilha Misson Rua Micheletti,José Batista Volpon,Virgínia Oliveira Crema +5 more
TL;DR: The results suggest that of tobacco smoke inhalation has a decreased of the cellular proliferation rate and altered morphology in submandibular glands de ratos Wistar.