Vincenzo Di Marzo
Laval University
709 Papers
4.8K Citations
Vincenzo Di Marzo is an academic researcher from Laval University. The author has contributed to research in topics: Endocannabinoid system & Cannabinoid receptor. The author has an hindex of 126, co-authored 659 publications. Previous affiliations of Vincenzo Di Marzo include National Research Council & University of Siena.
Chat about Author
Papers
Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands
Enrico Morera,Luciano De Petrocellis,Ludovica Morera,Aniello Schiano Moriello,Alessia Ligresti,Marianna Nalli,David F. Woodward,Vincenzo Di Marzo,Giorgio Ortar +8 more
TL;DR: The evaluation of a series of piperazinyl carbamates and ureas, designed on the basis of previously reported TRPV1 antagonists and FAAH inhibitors, led to the identification of some 'dual-action' compounds targeting both FAAH and TRpV1 or TRPA1 receptors.
35
Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueous Solubility.
Claudia Mugnaini,Antonella Brizzi,Alessia Ligresti,Marco Allarà,Stefania Lamponi,Federica Vacondio,Claudia Silva,Marco Mor,Vincenzo Di Marzo,Federico Corelli +9 more
TL;DR: Four-Quinolone-3-carboxamide derivatives have long been recognized as potent and selective cannabinoid type-2 receptor (CB2R) ligands, and the substitution of the alkyl chain with a basic replacement or scaffold modification to 4-hydroxy-2-quinolone structure enabled the discovery of a novel class of CB2R ligands.
35
Orexin-A and endocannabinoids are involved in obesity-associated alteration of hippocampal neurogenesis, plasticity, and episodic memory in mice.
Nicola Forte,Serena Boccella,Lea Tunisi,Alba Clara Fernández-Rilo,Roberta Imperatore,Fabio Arturo Iannotti,Maria De Risi,Monica Iannotta,Fabiana Piscitelli,Raffaele Capasso,Paolo de Girolamo,Elvira De Leonibus,Sabatino Maione,Vincenzo Di Marzo,Luigia Cristino +14 more
TL;DR: This paper showed that excessive orexin-A/2-arachidonoylglycerol/cannabinoid receptor type-1 signaling leads to the dysfunction of adult hippocampal neurogenesis and the subsequent inhibition of plasticity and impairment of pattern separation.
Effects of palmitoylethanolamide on the cutaneous allergic inflammatory response in Ascaris hypersensitive Beagle dogs.
Santiago Cerrato,Pilar Brazis,Maria Federica Della Valle,A. Miolo,Stefania Petrosino,Vincenzo Di Marzo,Anna Puigdemont +6 more
TL;DR: PEA might constitute a new therapeutic strategy for the treatment of allergic inflammatory skin diseases in companion animals because the anti-inflammatory effects of PEA were more long-lasting than their plasma concentrations.
34