Vinary Viswanadham
2 Papers
Vinary Viswanadham is an academic researcher. The author has contributed to research in topics: Exome sequencing & Medicine. The author has an hindex of 2, co-authored 2 publications.
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Papers
Comprehensive multi-omic profiling of somatic mutations in malformations of cortical development
Keng Ioi Vong,Swapnil Mittal,Catharina Donkels,H. Westley Phillips,Zhen Li,Ashley P L Marsh,Laurel L. Ball,Camila Araújo Bernardino Garcia,Renee D. George,Jing Gu,Mingchu Xu,Chelsea Barrows,Kiely N. James,Valentina Stanley,Anna S Nidhiry,Sami Khoury,Gabrielle Howe,Emily Riley,Xin Xu,Brett Copeland,Yifan Wang,Hoon Chul Kang,Andreas Schulze-Bonhage,Carola A. Haas,Horst Urbach,Marco Prinz,David D. Limbrick,Christina A. Gurnett,David D. Gonda,Katsumi Imai,Hsin Hung Chen,Valerio Conti,W. A. Silva,Hélio Rubens Machado,Sara Baldassari,Stéphanie Baulac,Diane Masser-Frye,Shifteh Sattar,Mark Nespeca,Yukitoshi Takahashi,J. Tsai,Renzo Guerrini,Orrin Devinsky,Se Hoon Kim,Hoon-Chul Kang,Yasemin Alanay,Seema Kapoor,Carola A. Haas,Georgia Ramantani,Thomas J. Feuerstein,I. Blumcke,Robyn M. Busch,Zhong Ying,Vadym Biloshytsky,Kostiantyn Kostiuk,Eugene Pedachenko,Gary W. Mathern,Matthew D. Smyth,Ingo Helbig,Benjamin C. Kennedy,Judy S. Liu,Felix Chan,Darcy A. Krueger,Richard Frye,Angus A. Wilfong,David L. Adelson,William Gaillard,Chima O. Oluigbo,Anne E. Anderson,August Yue Huang,Alissa M. D'Gama,Caroline Dias,Christopher A. Walsh,Javier Ganz,Michael A. Lodato,Michael Miller,Pengpeng Li,Rachel E. Rodin,R. Sean Hill,Sara Bizzotto,Sattar Khoshkhoo,Zinan Zhou,Alice Lee,Alison R. Barton,Alon Galor,C. Chu,Craig L. Bohrson,Doga Gulhan,Eduardo A Maury,Elaine T. Lim,Giorgio E. M. Melloni,Isidro Cortés,Jake Lee,Joe J Luquette,Lixing Yang,Maxwell A. Sherman,Michael E. Coulter,Minseok Kwon,Peter J. Park,Rebeca Borges-Monroy,Semin Lee,Sonia N. Kim,S. Lee,Vinary Viswanadham,Yanmei Dou,Andrew Chess,Attila G. Jones,Chaggai Rosenbluh,Schahram Akbarian,Ben Langmead,Jeremy Thorpe,Sea Eun Cho,Andrew E. Jaffe,Apuã C. M. Paquola,Daniel R. Weinberger,Jennifer A. Erwin,Joo Ho Shin,Michael J. McConnell,R. Straub,Rujuta Narurkar,Alexej Abyzov,Taejeong Bae,Yeongjun Jang,Anjené M. Addington,Geetha Senthil,Cindy Molitor,Mette A. Peters,Fred H. Gage,Mei-Ling Wang,Patrick Reed,Sara B. Linker,Alexander E. Urban,Bo Zhou,Reenal Pattni,Xiaowei Zhu,Aitor Serres Amero,David Juan,Inna S. Povolotskaya,Irene Lobon,Manuel Solis Moruno,Raquel Garcia Perez,Tomas Marques-Bonet,Eduardo Soriano,G D Mathern,Danny Antaki,Dan Averbuj,Eric Courchesne,Joseph G. Gleeson,Martin W. Breuss,Subhojit Roy,Xiaoxu Yang,Changuk Chung,Chen Sun,Diane Flasch,Trenton J. Frisbie Trenton,Huira C. Kopera,Jeffrey M. Kidd,John B. Moldovan,John V. Moran,Kenneth Y. Kwan,Ryan E. Mills,Sarah B. Emery,Weichen Zhou,Xuefang Zhao,Aakrosh Ratan,Adriana Cherskov,Alexandre Jourdon,Flora M. Vaccarino,Liana Fasching,Nenad Sestan,Sirisha Pochareddy,Soraya Scuder +171 more
TL;DR: In this article , the authors report a genetic landscape from 283 brain resections, identifying 69 mutated genes through intensive profiling of somatic mutations, combining whole-exome and targeted-amplicon sequencing with functional validation including in utero electroporation of mice and single-nucleus RNA sequencing.
Control-independent mosaic single nucleotide variant detection with DeepMosaic
Xiaoxu Yang,Xin Xu,Martin W. Breuss,Danny Antaki,Laurel L. Ball,Changuk Chung,Jiawei Shen,Chen Li,Renee D George,Yifan Wang,Taejeong Bae,Alexej Abyzov,Liping Wei,Ludmil B. Alexandrov,Jonathan Sebat,Dan Averbuj,Subhojit Roy,Eric Courchesne,August Yue Huang,Alissa M. D'Gama,Caroline Dias,Christopher A. Walsh,Javier Ganz,Michael A. Lodato,Pengpeng Li,Rachel E. Rodin,R. Sean Hill,Sara Bizzotto,Sattar Khoshkhoo,Zinan Zhou,Alice Lee,Alison R. Barton,Alon Galor,C. Chu,Craig L. Bohrson,Doga Gulhan,Eduardo A Maury,Elaine Lim,Giorgio E. M. Melloni,Isidro Cortés,Jake Lee,Joe J Luquette,Lixing Yang,Maxwell A. Sherman,Michael E. Coulter,Minseok Kwon,Peter J. Park,Rebeca Borges-Monroy,Semin Lee,Sonia N. Kim,S. Lee,Vinary Viswanadham,Yanmei Dou,Andrew Chess,Attila G. Jones,Chaggai Rosenbluh,Schahram Akbarian,Ben Langmead,Jeremy Thorpe,Sea Eun Cho,Andrew E. Jaffe,Apuã C. M. Paquola,Daniel R. Weinberger,Jennifer A. Erwin,Joo Ho Shin,Michael J. McConnell,R. Straub,Rujuta Narurkar,Yeongjun Jang,Cindy Molitor,Mette A. Peters,Fred H. Gage,Mei-Ling Wang,Patrick Reed,Sara B. Linker,Alexander E. Urban,Bo Zhou,Xiaowei Zhu,Aitor Serres Amero,David Juan,Inna S. Povolotskaya,Irene Lobon,Manuel Solis Moruno,Raquel Garcia Perez,Tomas Marques-Bonet,Eduardo Soriano,G D Mathern,Diane Flasch,Trent Frisbie,Huira C. Kopera,Jeffrey N Kidd,John B. Moldovan,John V. Moran,Kenneth Kwan,Ryan E. Mills,Sarah B. Emery,Weichen Zhou,Xuefang Zhao,Aakrosh Ratan,Alexandre Jourdon,Flora M. Vaccarino,Liana Fasching,Nenad Sestan,Sirisha Pochareddy,Soraya Scuderi,Joseph G. Gleeson +105 more
TL;DR: DeepMosaic is presented, combining an image-based visualization module for single nucleotide MVs and a convolutional neural network-based classification module for control-independent MV detection that represents an accurate MV classifier for noncancer samples that can be implemented as an alternative or complement to existing methods.