Vikash Kumar
Medical College of Wisconsin
16 Papers
24 Citations
Vikash Kumar is an academic researcher from Medical College of Wisconsin. The author has contributed to research in topics: Kidney & mTORC1. The author has an hindex of 9, co-authored 14 publications. Previous affiliations of Vikash Kumar include Cleveland Clinic Lerner Research Institute & Cleveland Clinic.
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Papers
Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats.
Allen W. Cowley,Chun Yang,Nadezhda N. Zheleznova,Alexander Staruschenko,Theresa Kurth,Lisa Rein,Vikash Kumar,Katherine Sadovnikov,Alex Dayton,Matthew Hoffman,Robert P. Ryan,Meredith M. Skelton,Fahimeh Salehpour,Mahsa Ranji,Aron M. Geurts +14 more
TL;DR: It is concluded that the reduced renal injury and attenuated blood pressure response to high salt in the SSNox4−/− rat could be the result of multiple pathways, including gene transcription, mitochondrial energetics, oxidative stress, and protein matrix production impacted by the knock out of Nox4.
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Interaction between coat protein and replication initiation protein of Mung bean yellow mosaic India virus might lead to control of viral DNA replication.
TL;DR: A reasonably strong interaction between Rep and CP of the geminivirus Mung bean yellow mosaic India virus is reported, highlighting how CP could be important in controlling geminaviral DNA replication.
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MicroRNAs are critical regulators of tuberous sclerosis complex and mTORC1 activity in the size control of the Xenopus kidney.
TL;DR: It is shown for the first time, to the knowledge, that growth factors belonging to the Insulin growth factor family are critically important in establishing kidney size and that the strength of the signal is dependent on the presence of small noncoding RNAs termed microRNAs.
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The bigger the better: determining nephron size in kidney
TL;DR: Recent studies that highlight the early phases of kidney development as a critical juncture in establishing proximal tubule size are summarized.
Tomato leaf curl New Delhi virus (ToLCNDV) encoded AC2 associates with host mirnas by directly interacting with AGO1
Vikash Kumar,Vikash Kumar,Afsar R Naqvi +2 more
- 01 Jan 2016
TL;DR: It is found that AC2 associates with miR319 and miR172 which are deregulated during ToLCNDV infection and this association was mediated by direct interaction of AC2 with AGO1 using in vitro and ex vivo assays, providing mechanistic insight on understanding of AC1-mediated deregulation of host miRNA pathway.