Victoria Smith
University of Liverpool
5 Papers
Victoria Smith is an academic researcher from University of Liverpool. The author has contributed to research in topics: Translation (biology) & Medicine. The author has an hindex of 2, co-authored 3 publications.
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Papers
poly(I:C) synergizes with proteasome inhibitors to induce apoptosis in cervical cancer cells
Xue Meng,Xiaoxi Cui,Xiaoyan Shao,Yanqi Liu,Yihao Xing,Victoria Smith,Shiqiu Xiong,Salvador Macip,Yixiang Chen +8 more
TL;DR: In this paper , dsRNA poly(I:C) upregulated the expression of IFNβ and apoptosis-associated genes in cervical cancer cells, activating both intrinsic and extrinsic apoptotic pathways, and eventually inducing cell death.
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The deubiquitylase USP9X controls ribosomal stalling
Anne Clancy,Claire Heride,Adan Pinto-Fernandez,Hannah Elcocks,Andreas Kallinos,Katherine J. Kayser-Bricker,Weiping Wang,Victoria Smith,Simon J. Davis,Shawn Fessler,Crystal McKinnon,Marie Katz,Tim Hammonds,Neil P. Jones,Jonathan O'Connell,Bruce Follows,Steven Mischke,Caravella Justin Andrew,Stephanos Ioannidis,Christopher J. Dinsmore,Sunkyu Kim,Axel Behrens,David Komander,David Komander,Benedikt M. Kessler,Sylvie Urbé,Michael J. Clague +26 more
TL;DR: In this article, a small-molecule inhibitor of the deubiquitylase USP9X has been developed, which results in a loss of Makorin 2 and ZNF598.
RecJ3/4-aRNase J form a Ubl-associated nuclease complex functioning in survival against DNA damage in Haloferax volcanii
Huiyong Jia,Swathi Dantuluri,Shae Margulies,Victoria Smith,Rebecca Lever,Thorsten Allers,Jin Koh,Sixue Chen,Julie A. Maupin-Furlow +8 more
TL;DR: In this article , a new type of nuclease complex, composed of RecJ3, RecJ4, and aRNase J, was identified through its ATP-dependent association with the ubiquitin-like SAMP1 and AAA-ATPase Cdc48a.
Correction: The deubiquitylase USP9X controls ribosomal stalling
Anne Clancy,Claire Heride,Adan Pinto-Fernandez,Hannah Elcocks,Andreas Kallinos,Katherine J. Kayser-Bricker,Weiping Wang,Victoria Smith,Simon J. Davis,Shawn Fessler,Crystal McKinnon,Marie Katz,Tim Hammonds,Neil P. Jones,Jonathan O'Connell,Bruce Follows,Steven Mischke,Caravella Justin Andrew,Stephanos Ioannidis,Christopher J. Dinsmore,Sunkyu Kim,Axel Behrens,David Komander,Benedikt M. Kessler,Sylvie Urbé,Michael J. Clague +25 more
The deubiquitylase USP9X controls ribosomal stalling
Anne Clancy,Claire Heride,Adan Pinto-Fernandez,Andreas Kallinos,Katherine J. Kayser-Bricker,Weiping Wang,Victoria Smith,Hannah Elcocks,Simon J. Davis,Shawn Fessler,Crystal McKinnon,Marie Katz,Tim Hammonds,Neil P. Jones,Jonathan O'Connell,Bruce Follows,Steven Mischke,Caravella Justin Andrew,Stephanos Ioannidis,Christopher J. Dinsmore,Sunkyu Kim,Axel Behrens,David Komander,David Komander,Benedikt M. Kessler,Sylvie Urbé,Michael J. Clague +26 more
TL;DR: Proteomics analysis, following inhibitor treatment of HCT116 cells, confirms previous reports linking USP9X with centrosome associated protein stability and reveals loss of ZNF598 and Makorin 2.