Vicky Yao
Rice University
6 Papers
Vicky Yao is an academic researcher from Rice University. The author has contributed to research in topics: Computer science & Medicine. The author has an hindex of 3, co-authored 5 publications. Previous affiliations of Vicky Yao include Howard Hughes Medical Institute & Princeton University.
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Papers
RNA Identification of PRIME Cells Predicting Rheumatoid Arthritis Flares
Dana E. Orange,Dana E. Orange,Vicky Yao,Vicky Yao,Vicky Yao,Kirsty Sawicka,John J. Fak,Mayu O. Frank,Salina Parveen,Nathalie E. Blachere,Caryn R Hale,Fan Zhang,Fan Zhang,Soumya Raychaudhuri,Soumya Raychaudhuri,Olga G. Troyanskaya,Robert B. Darnell +16 more
TL;DR: Longitudinal genomic analysis of rheumatoid arthritis flares revealed PRIME cells in the blood during the period before a flare and suggested a model in which these cells become activated by B cells inThe weeks before a flares and subsequently migrate out of the blood into the synovium.
165
Selective Neuronal Vulnerability in Alzheimer's Disease: A Network-Based Analysis.
Jean-Pierre Roussarie,Vicky Yao,Vicky Yao,Patricia Rodriguez-Rodriguez,Patricia Rodriguez-Rodriguez,Rose Oughtred,Jennifer M. Rust,Zakary Plautz,Shirin Kasturia,Christian Albornoz,Wei Wang,Eric F. Schmidt,Ruth Dannenfelser,Alicja Tadych,Lars Brichta,Alona Barnea-Cramer,Nathaniel Heintz,Patrick R. Hof,Myriam Heiman,Myriam Heiman,Myriam Heiman,Kara Dolinski,Marc Flajolet,Olga G. Troyanskaya,Paul Greengard +24 more
TL;DR: A framework integrating high-quality neuron-type-specific molecular profiles across the lifetime of the healthy mouse, generated using bacTRAP, with postmortem human functional genomics and quantitative genetics data is presented.
160
Discriminatory Power of Combinatorial Antigen Recognition in Cancer T Cell Therapies
Ruth Dannenfelser,Gregory M. Allen,Benjamin VanderSluis,Ashley K. Koegel,Sarah Levinson,Sierra R. Stark,Vicky Yao,Vicky Yao,Alicja Tadych,Olga G. Troyanskaya,Wendell A. Lim +10 more
TL;DR: This work demonstrates the potential of 2- to 3-antigen Boolean logic gates for improving tumor discrimination by CAR T cell therapies and identifies antigen triplets that are predicted to show close to ideal tumor-versus-normal tissue discrimination for several tumor types.
75
Neuron-Glia Signaling Regulates the Onset of the Antidepressant Response
Vicky Yao,Ammar Aly,Salina Kalik,Jodi Gresack,Wei Wang,Annie Handler,Anne Schaefer,Olga G. Troyanskaya,Paul Greengard,Revathy U. Chottekalapanda +9 more
TL;DR: In this paper, a single cell sequencing approach was used to analyze gene expression changes in mice subjected to stress-induced depression and determined their temporal response to antidepressant treatment in the cerebral cortex.
A loop-counting method for covariate-corrected low-rank biclustering of gene-expression and genome-wide association study data
Aaditya V. Rangan,Caroline C. McGrouther,John R. Kelsoe,Nicholas J. Schork,Eli A. Stahl,Qian Zhu,Arjun Krishnan,Vicky Yao,Olga G. Troyanskaya,Seda Bilaloglu,Preeti Raghavan,Sarah E. Bergen,Anders Juréus,Anders Juréus,Mikael Landén +14 more
TL;DR: This paper presents a simple algorithm for tackling biclustering in data-analysis, which accumulates information about 2-by-2 submatrices within the data-matrix, and focuses on rows and columns that participate in an abundance of low-rank loops.