Vetvicka
1 Papers
Vetvicka is an academic researcher. The author has contributed to research in topics: Cytotoxic T cell & Phagocytosis. The author has an hindex of 1, co-authored 1 publications.
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Papers
•Journal Article
The beta-glucan-binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to iC3b-opsonized target cells.
TL;DR: Mouse leukocyte CR3 (Mac-1, alphaMbeta2 integrin) was shown to function as a receptor for beta-glucans in the same way as human CR3, and the similarity of mouse and humanCR3 in response to beta-Glucans highlights the utility of mouse tumor models for development of therapeutic beta- glucans.
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