Veronika von Messling
Paul Ehrlich Institute
92 Papers
671 Citations
Veronika von Messling is an academic researcher from Paul Ehrlich Institute. The author has contributed to research in topics: Virus & Measles virus. The author has an hindex of 34, co-authored 85 publications. Previous affiliations of Veronika von Messling include Université du Québec & Federal Ministry of Education and Research.
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Papers
Utilising animal models to evaluate oseltamivir efficacy against influenza A and B viruses with reduced in vitro susceptibility.
Rubaiyea Farrukee,Celeste Ming-Kay Tai,Ding Yuan Oh,Ding Yuan Oh,Danielle E. Anderson,Vithiagaran Gunalan,Martin L. Hibberd,Gary Yuk-Fai Lau,Ian G. Barr,Ian G. Barr,Veronika von Messling,Veronika von Messling,Sebastian Maurer-Stroh,Sebastian Maurer-Stroh,Sebastian Maurer-Stroh,Aeron C. Hurt +15 more
TL;DR: Analysis of the ferret data revealed a correlation between IC50 and OST efficacy in reducing viral shedding but highlighted that the current WHO guidelines/criteria for defining normal, reduced or highly reduced inhibition in influenza B viruses based on in vitro data are not well aligned with the low in vivo O ST efficacy observed.
Generation of therapeutic antisera for emerging viral infections.
Rebecca Schmidt,Lea C Beltzig,Bevan Sawatsky,Olga Dolnik,Erik Dietzel,Verena Krähling,Asisa Volz,Gerd Sutter,Stephan Becker,Veronika von Messling +9 more
- 05 Oct 2018
TL;DR: Comparing different vaccination platforms in mice and rabbits finds that following multiple vaccine challenges, neutralizing antibody titers equivalent to that seen in convalescent patients could be obtained, offering the hope of rapidly generating large quantities of neutralizing anti-serum that could be used in a viral outbreak scenario.
Assessment of the Efficacy of Commercially Available and Candidate Vaccines against a Pandemic H1N1 2009 Virus
Gary P. Kobinger,Gary P. Kobinger,Isabelle Meunier,Ami Patel,Ami Patel,Stéphane Pillet,Jason Gren,Shane Stebner,Anders Leung,James Neufeld,Darwyn Kobasa,Darwyn Kobasa,Veronika von Messling +12 more
TL;DR: It is demonstrated that a single dose of matched inactivated vaccine confers partial protection against a pandemic H1N1 2009 virus, and it suggests that a higher dose or prime-boost regimen may be required.
Influenza pathogenesis: lessons learned from animal studies with H5N1, H1N1 Spanish, and pandemic H1N1 2009 influenza.
TL;DR: published studies reveal the importance of early treatment with antivirals and show the potential and limitations of approaches aimed at the host response, and point to an important role for immune dysregulation in the pathogenesis of highly pathogenic influenza.
Inactivated Recombinant Rabies Viruses Displaying Canine Distemper Virus Glycoproteins Induce Protective Immunity against Both Pathogens.
Renata da Fontoura Budaszewski,Renata da Fontoura Budaszewski,Andrew W. Hudacek,Bevan Sawatsky,Beate Krämer,Xiangping Yin,Matthias J. Schnell,Veronika von Messling +7 more
TL;DR: Recombinant inactivated rabies viruses that carry one of the CDV glycoproteins on their surface are generated, illustrating that a bivalent rabies virus-based vaccine against CDV induces protective immune responses against both pathogens.