Veronica Yim
University of Toronto
3 Papers
1 Citations
Veronica Yim is an academic researcher from University of Toronto. The author has contributed to research in topics: Hypothetical protein & Metagenomics. The author has an hindex of 2, co-authored 3 publications.
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Papers
Activity screening of environmental metagenomic libraries reveals novel carboxylesterase families.
Ana Popovic,Tran Hai,Anatoly Tchigvintsev,Mahbod Hajighasemi,Boguslaw Nocek,Anna N. Khusnutdinova,Greg Brown,Julia Glinos,Robert Flick,Tatiana Skarina,Tatyana N. Chernikova,Veronica Yim,Thomas Brüls,Denis Le Paslier,Michail M. Yakimov,Andrzej Joachimiak,Manuel Ferrer,Olga V. Golyshina,Alexei Savchenko,Peter N. Golyshin,Alexander F. Yakunin +20 more
TL;DR: Activity-centered metagenomics has revealed diverse enzymes and novel families of microbial carboxylesterases, whose activity could not have been predicted using bioinformatics tools.
Experimental validation of in silico model-predicted isocitrate dehydrogenase and phosphomannose isomerase from Dehalococcoides mccartyi
M. Ahsanul Islam,Anatoli Tchigvintsev,Veronica Yim,Alexei Savchenko,Alexander F. Yakunin,Radhakrishnan Mahadevan,Elizabeth A. Edwards +6 more
TL;DR: In this paper, the authors reported the experimental validation of the proposed reannotations for two such genes (KB1_0495 and KB1_0553) from D.mccartyi strains in the KB-1 community.
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In situ proteolysis for protein crystallization and structure determination
Aiping Dong,Xiaohui Xu,Aled M. Edwards,Changsoo Chang,Maksymilian Chruszcz,Marianne Cuff,Marcin Cymborowski,Rosa Di Leo,Olga Egorova,Elena Evdokimova,Ekaterina V. Filippova,Jun Gu,Jennifer L. Guthrie,Alexandr Ignatchenko,Andrzej Joachimiak,Natalie R Klostermann,Youngchang Kim,Yuri Korniyenko,Wladek Minor,Qiuni Que,Alexei Savchenko,Tatiana Skarina,Kemin Tan,Alexander F. Yakunin,Adelinda Yee,Veronica Yim,Rongguang Zhang,Hong Zheng,Masato Akutsu,Cheryl H. Arrowsmith,George V. Avvakumov,Alexey Bochkarev,Lars Göran Dahlgren,Sirano Dhe-Paganon,Slav Dimov,Ludmila Dombrovski,P.J. Finerty,Susanne Flodin,A. Flores,Susanne Gräslund,Martin Hammerström,Maria Dolores Herman,Bum Soo Hong,Raymond Hui,Ida Johansson,Yongson Liu,Martina Nilsson,Lyudmila Nedyalkova,P. Nordlund,Tomas Nyman,Jinrong Min,Hui Ouyang,Hee-Won Park,Chao Qi,Wael M. Rabeh,Limin Shen,Yang Shen,Deepthi Sukumard,Wolfram Tempel,Yufeng Tong,Lionel Tresagues,Masoud Vedadi,John R. Walker,Johan Weigelt,Martin Welin,Hong Wu,Ting Xiao,Hong Zeng,Haizhong Zhu +68 more
TL;DR: The general applicability of in situ proteolysis to form protein crystals suitable for structure determination is tested by adding a protease (chymotrypsin or trypsin) digestion step to crystallization trials of 55 bacterial and 14 human proteins that had proven recalcitrant to best efforts at crystallization or structure determination.