Venkappayya Devashya
Shanmugha Arts, Science, Technology & Research Academy
6 Papers
14 Citations
Venkappayya Devashya is an academic researcher from Shanmugha Arts, Science, Technology & Research Academy. The author has contributed to research in topics: Lipid bilayer & Bilayer. The author has an hindex of 6, co-authored 6 publications.
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Papers
Flavonoid-metal ion complexes: a novel class of therapeutic agents
Stalin Selvaraj,Sridharan Krishnaswamy,Venkappayya Devashya,Swaminathan Sethuraman,Uma Maheswari Krishnan +4 more
TL;DR: A snapshot of the various biological activities reported for flavonoid–metal ion complexes and their potential as therapeutic agents is provided to provide a snapshot of their molecular targets and mechanisms of action.
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Influence of membrane lipid composition on flavonoid-membrane interactions: Implications on their biological activity.
Stalin Selvaraj,Sridharan Krishnaswamy,Venkappayya Devashya,Swaminathan Sethuraman,Uma Maheswari Krishnan +4 more
TL;DR: This review highlights different techniques employed and attempts to correlate the membrane localization and alteration in membrane fluidity with the biological activities of flavonoids such as anti-oxidant, anti-cancer and anti-microbial properties.
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Investigations on membrane perturbation by chrysin and its copper complex using self-assembled lipid bilayers.
Stalin Selvaraj,Sridharan Krishnaswamy,Venkappayya Devashya,Swaminathan Sethuraman,Uma Maheswari Krishnan +4 more
TL;DR: The results demonstrate that, at low concentrations, the chrysin-copper complex exhibited twice the protection against hypotonic stress-induced membrane disruption when compared to chrysIn, however, this stabilizing effect gradually decreased and became comparable toChrysin at higher concentrations, which could further be explored for therapeutic applications.
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Synthesis, characterization and DNA binding properties of rutin–iron complex
Stalin Selvaraj,Sridharan Krishnaswamy,Venkappayya Devashya,Swaminathan Sethuraman,Uma Maheswari Krishnan +4 more
TL;DR: The results indicate the potential of the rutin–iron complex as an anti-cancer agent and the intercalative mode of interaction for both compounds is confirmed.
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Investigations on the membrane interactions of naringin and its complexes with copper and iron: implications for their cytotoxicity
Stalin Selvaraj,Sridharan Krishnaswamy,Venkappayya Devashya,Swaminathan Sethuraman,Uma Maheswari Krishnan +4 more
TL;DR: The copper and iron complexes of naringin exhibit superior cytotoxicity against MCF-7 cancer cells that can be a manifestation of their degree of perturbation of the membrane architecture as well as different levels of activation of various molecular targets.
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