Valérie Fontaine
Vision Institute
20 Papers
158 Citations
Valérie Fontaine is an academic researcher from Vision Institute. The author has contributed to research in topics: Retina & Retinal. The author has an hindex of 11, co-authored 18 publications. Previous affiliations of Valérie Fontaine include Pierre-and-Marie-Curie University & University of Stuttgart.
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Papers
Neurodegenerative and neuroprotective effects of tumor Necrosis factor (TNF) in retinal ischemia: opposite roles of TNF receptor 1 and TNF receptor 2.
Valérie Fontaine,Saddek Mohand-Said,Noelle Hanoteau,Céline Fuchs,Klaus Pfizenmaier,Ulrich L. M. Eisel +5 more
TL;DR: Early, transient upregulation of TNF, TNF receptor 1, and TNF-R1 6 hr after reperfusion preceding neuronal cell loss in retinal ischemia is shown, indicating an instrumental role of Akt/PKB in neuroprotection and T NF-R2 dependence of this pathway.
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Functional cone rescue by RdCVF protein in a dominant model of retinitis pigmentosa.
Ying Yang,Ying Yang,Saddek Mohand-Said,Saddek Mohand-Said,Aude Danan,Manuel Simonutti,Manuel Simonutti,Valérie Fontaine,Valérie Fontaine,Emmanuelle Clérin,Emmanuelle Clérin,Serge Picaud,Serge Picaud,Thierry Léveillard,Thierry Léveillard,José-Alain Sahel +15 more
TL;DR: The demonstration at the functional level of the therapeutic potential of Rd CVF in the most frequent of dominant RP mutations paves the way toward the use of RdCVF for preserving central vision in many RP patients.
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Phototoxic action spectrum on a retinal pigment epithelium model of age-related macular degeneration exposed to sunlight normalized conditions.
Emilie Arnault,Emilie Arnault,Emilie Arnault,Coralie Barrau,Céline Nanteau,Céline Nanteau,Céline Nanteau,Pauline Gondouin,Pauline Gondouin,Pauline Gondouin,Karine Bigot,Karine Bigot,Karine Bigot,Françoise Viénot,Emmanuel Gutman,Emmanuel Gutman,Emmanuel Gutman,Valérie Fontaine,Valérie Fontaine,Valérie Fontaine,Thierry Villette,Denis Cohen-Tannoudji,José-Alain Sahel,Serge Picaud +23 more
TL;DR: Surprisingly, a narrow bandwidth in blue light generated the greatest phototoxic risk to retinal pigment epithelium cells, and may be advantageously valued in designing selective photoprotection ophthalmic filters, without disrupting essential visual and non-visual functions of the eye.
Survival of Purified Rat Photoreceptors In Vitro Is Stimulated Directly by Fibroblast Growth Factor-2
TL;DR: In this paper, the outer nuclear layers of postnatal day 5-15 rat retinas were isolated by vibratome sectioning, and the photoreceptor fractions obtained were enzymatically dissociated.
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•Journal Article
Differential distribution of dystrophins in rat retina
Thomas Claudepierre,Frangois Rodius,Maria Frasson,Valérie Fontaine,Serge Picaud,Henri Dreyfus,Dominique Mornet,Alvaro Rendon +7 more
TL;DR: The hypothesis that b-wave reduction may be caused by molecular anomalies of C-terminal products of the dystrophin gene expressed in both neuron and glial cells is supported.
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