V. Rocher
Queen Mary University of London
10 Papers
12 Citations
V. Rocher is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Rheumatoid arthritis & Synovitis. The author has an hindex of 3, co-authored 10 publications.
Chat about Author
Papers
Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients
Frances Humby,Myles Lewis,Nandhini Ramamoorthi,Jason A. Hackney,Michael R. Barnes,Michele Bombardieri,A. Francesca Setiadi,Stephen Kelly,F Bene,M DiCicco,Sudeh Riahi,V. Rocher,Nora Ng,Ilias Lazarou,Rebecca Hands,Désirée van der Heijde,Robert Landewé,Annette H M van der Helm-van Mil,Alberto Cauli,Iain B. McInnes,Christopher D. Buckley,Ernest Choy,Peter C. Taylor,Michael J. Townsend,Costantino Pitzalis +24 more
TL;DR: At disease presentation, prior to pathology modulation by therapy, the presence of specific cellular/molecular synovial signatures that delineate disease severity/progression and therapeutic response may pave the way to more precise definition of RA taxonomy, therapeutic targeting and improved outcomes.
266
OP0040 Synovial cell infiltration in acpa-ve patients displays similar signatures to other seronegative inflammatory arthritis. results from the pathobiology of early arthritis cohort (PEAC)
Gloria Lliso-Ribera,Frances Humby,Alessandra Nerviani,Marie-Astrid Boutet,Stephen Kelly,Michele Bombardieri,Myles Lewis,Rebecca Hands,V. Rocher,F Bene,Christopher D. Buckley,Peter C. Taylor,Iain B. McInnes,C. Pitzalis +13 more
TL;DR: This study examines in a cohort of therapy naïve, early inflammatory arthritis patients whether ACPA-ve RA can be defined at disease initiation according to synovial pathobiological signatures and suggests shared pathophysiological mechanisms between PsA and ACPA -ve RA and support a role for future refinement of diagnosis.
OP0054 Ultrasound Synovitis Reflects Synovial Inflammation at A Histopathological Level
TL;DR: The results have shown that US PD also reflects synovial inflammation at a histopathological level, and supports the current opinion that Power Doppler US is a biomarker for treatment response and reflects both clinical and histological markers of disease activity in patients with RA.
3
Synovial lymphocytic aggregates associate with highly active ra and predict erosive disease progression at 12 months: results from the pathobiology of early arthritis cohort
M DiCicco,Frances Humby,S Kelly,Michele Bombardieri,H Rebecca,V. Rocher,Lu Zou,L. Myles,Arti Mahto,K. Blighe,Nora Ng,Iain B. McInnes,Peter C. Taylor,Robert Landewé,A Van der Helm-Van Mil,D. van der Heijde,Costantino Pitzalis +16 more
1
101. Synovial Ectopic Lymphoneogenesis Predicts Primary Clinical Response to Certolizumab Pegol in Patients with Rheumatoid Arthritis
Maria Di Cicco,Stephen Kelly,Frances Humby,Nora Ng,Rebecca Hands,V. Rocher,Alessandra Nerviani,Lu Zou,Michele Bombardieri,Costantino Pitzalis +9 more
TL;DR: A.R. is a consultant for BristolMyers Squibb, Abbott, Chugai, UCB, Essex, Wyeth, Pfizer, MSD, Novartis and Roche; and is a member of a speakers’ bureau for Bristol-MyersSquibb.
1