Usanee Khunarkornsiri
10 Papers
Usanee Khunarkornsiri is an academic researcher. The author has contributed to research in topics: Toxic epidermal necrolysis & Human leukocyte antigen. The author has an hindex of 7, co-authored 10 publications.
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Papers
HLA Pharmacogenetic Markers of Drug Hypersensitivity in a Thai Population
Nontaya Nakkam,Parinya Konyoung,Sirimas Kanjanawart,Niwat Saksit,Thachanan Kongpan,Kanyarat Khaeso,Usanee Khunarkornsiri,Areerat Dornsena,Wongwiwat Tassaneeyakul,Wichittra Tassaneeyakul +9 more
TL;DR: Based on the frequencies of HLA pharmacogenetic markers, Thai and other Southeast Asian populations may be at higher risk of drug-induced SCARs compared with Caucasian population.
Candidate HLA genes for prediction of co-trimoxazole-induced severe cutaneous reactions.
Thachanan Kongpan,Surakameth Mahasirimongkol,Parinya Konyoung,Sirimas Kanjanawart,Pansu Chumworathayi,Nuanjun Wichukchinda,Runglak Kidkeukarun,Suphanlinee Preechakul,Usanee Khunarkornsiri,Warawut Bamrungram,Butsaban Supharatwattanakun,Piroon Mootsikapun,Supanida Kwangsukstid,Sukanda Denjanta,Suda Vannaprasaht,Watcharee Rungapiromnan,Wimon Suwankesawong,Wongwiwat Tassaneeyakul,Wichittra Tassaneeyakul +18 more
TL;DR: The findings may suggest that apart from the HLA molecules, other molecules involved in the molecular pathogenesis of these severe cutaneous adverse drug reactions may play an important role in the susceptibility of individuals to SJS/TEN caused by co-trimoxazole.
Association between HLA-B*1502 and carbamazepine-induced severe cutaneous adverse drug reactions in a Thai population
Wichittra Tassaneeyakul,Somsak Tiamkao,Thawinee Jantararoungtong,Pei Chen,Shu Yi Lin,Wei Hsuan Chen,Parinya Konyoung,Usanee Khunarkornsiri,Narong Auvichayapat,Kasemsin Pavakul,Kongkiat Kulkantrakorn,Charoen Choonhakarn,Siranun Phonhiamhan,Namfon Piyatrakul,Thiti Aungaree,Sunsanee Pongpakdee,Praphan Yodnopaglaw +16 more
TL;DR: Results from this study suggest that HLA‐B*1502 may be a useful pharmacogenetic test for screening Thai individuals who may be at risk for CBZ‐induced SJS and TEN.
Associations between HLA class I and cytochrome P450 2C9 genetic polymorphisms and phenytoin-related severe cutaneous adverse reactions in a Thai population
Wichittra Tassaneeyakul,Napat Prabmeechai,Chonlaphat Sukasem,Thachanan Kongpan,Parinya Konyoung,Pansu Chumworathayi,Somsak Tiamkao,Usanee Khunarkornsiri,Kongkiat Kulkantrakorn,Niwat Saksit,Nontaya Nakkam,Patompong Satapornpong,Suda Vannaprasaht,Alisara Sangviroon,Surakameth Mahasirimongkol,Nuanjun Wichukchinda,Ticha Rerkpattanapipat,Wongwiwat Tassaneeyakul +17 more
TL;DR: Certain alleles of HLA, particularly HLA-B*56:02, were significantly associated with phenytoin-related SCAR in the study population, and these alleles were observed in patients with CYP2C9*3, but not DRESS.
Genetic Association of Co-Trimoxazole-Induced Severe Cutaneous Adverse Reactions Is Phenotype-Specific: HLA Class I Genotypes and Haplotypes.
Chonlaphat Sukasem,Jirawat Pratoomwun,Patompong Satapornpong,Patompong Satapornpong,Jettanong Klaewsongkram,Jettanong Klaewsongkram,Ticha Rerkpattanapipat,Pawinee Rerknimitr,Pattamon Lertpichitkul,Apichaya Puangpetch,Nontaya Nakkam,Parinya Konyoung,Usanee Khunarkornsiri,Wareeporn Disphanurat,Chutika Srisuttiyakorn,Oranuch Pattanacheewapull,Sirimas Kanjanawart,Thachanan Kongpan,Pansu Chumworathayi,Niwat Saksit,Jackrapong Bruminhent,Wichittra Tassaneeyakul,Wasun Chantratita,Munir Pirmohamed +23 more
TL;DR: It is demonstrated that genetic association of CTX‐induced SCARs was phenotype‐specific, and Interestingly, these association was observed only in HIV‐infected patients but not in non‐HIV‐ Infected patients.