Uri Weill
Weizmann Institute of Science
15 Papers
36 Citations
Uri Weill is an academic researcher from Weizmann Institute of Science. The author has contributed to research in topics: Proteome & Biology. The author has an hindex of 10, co-authored 14 publications.
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Papers
Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale
Marcel Morgenstern,Sebastian B. Stiller,Philipp Lübbert,Christian D. Peikert,Stefan Dannenmaier,Friedel Drepper,Uri Weill,Philipp Höß,Reinhild Feuerstein,Michael Gebert,Maria Bohnert,Martin van der Laan,Maya Schuldiner,Conny Schütze,Silke Oeljeklaus,Nikolaus Pfanner,Nils Wiedemann,Bettina Warscheid +17 more
TL;DR: The integrative proteome provides a high-confidence source for the characterization of physiological and pathophysiological functions of mitochondria and their integration into the cellular environment.
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Genome-wide SWAp-Tag yeast libraries for proteome exploration
Uri Weill,Ido Yofe,Ehud Sass,Bram Stynen,Dan Davidi,Janani Natarajan,Reut Ben-Menachem,Zohar Avihou,Omer Goldman,Nofar Harpaz,Silvia G. Chuartzman,Kiril Kniazev,Barbara Knoblach,Janina Laborenz,Felix Boos,Jacqueline Kowarzyk,Shifra Ben-Dor,Einat Zalckvar,Johannes M. Herrmann,Richard A. Rachubinski,Ophry Pines,Doron Rapaport,Stephen W. Michnick,Emmanuel D. Levy,Maya Schuldiner +24 more
TL;DR: This work constructed a genome-wide library of ~5,500 strains carrying the SWAT NOP1promoter-GFP module at the N terminus of proteins, and created six diverse libraries that restored the native regulation, created an overexpression library with a Cherry tag, or enabled protein complementation assays from two fragments of an enzyme or fluorophore.
Assessment of GFP Tag Position on Protein Localization and Growth Fitness in Yeast.
TL;DR: This study uses a competition-based approach to decipher the relative fitness of two strains tagged on the same protein but on opposite termini and from that infer the correct, physiological localization for each protein and the optimal position for tagging.
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Pex35 is a regulator of peroxisome abundance.
Ido Yofe,Kareem Soliman,Silvia G. Chuartzman,Bruce A. Morgan,Bruce A. Morgan,Uri Weill,Eden Yifrach,Tobias P. Dick,Sara J. Cooper,Christer S. Ejsing,Maya Schuldiner,Einat Zalckvar,Sven Thoms +12 more
TL;DR: High-content screens identify Pex35, a new peroxisomal membrane protein that regulates peroxISome abundance in yeast and reveals the functional interaction betweenperoxisomes and the secretory pathway.
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Mice lacking WRB reveal differential biogenesis requirements of tail-anchored proteins in vivo.
Jhon Rivera-Monroy,Lena Musiol,Kirsten Unthan-Fechner,Ákos Farkas,Anne Clancy,Javier Coy-Vergara,Uri Weill,Sarah Gockel,Shuh-Yow Lin,David P. Corey,Tobias Kohl,Philipp Ströbel,Maya Schuldiner,Blanche Schwappach,Fabio Vilardi +14 more
TL;DR: The results highlight an intimate relationship between the TRC40 pathway and cellular proteostasis and establish that Stx5 is an autophagy target that is inefficiently membrane-targeted by alternative pathways.