Ulrike Holzgrabe
University of Würzburg
593 Papers
3.8K Citations
Ulrike Holzgrabe is an academic researcher from University of Würzburg. The author has contributed to research in topics: Chemistry & Allosteric regulation. The author has an hindex of 45, co-authored 566 publications. Previous affiliations of Ulrike Holzgrabe include Jagiellonian University & University of Illinois at Chicago.
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Papers
Studies on the stereochemistry of 1,2,6-trimethyl-4-piperidone
TL;DR: In this paper, a cis/trans mixture of 1,2,6-trimethyl-4-piperidone was investigated and the potential energy surface of the equilibration process of the trans-isomer was determined by quantum chemical calculations.
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Impurity profiling of l-aspartic acid and glycine using high-performance liquid chromatography coupled with charged aerosol and ultraviolet detection.
TL;DR: Coupled charged aerosol and UV detection proved to be a more simple, robust and selective alternative to established derivatization procedures such as the Amino-Acid-Analyser (AAA) for the impurity profiling of amino acids, and should thus be considered for implementation into pharmacopoeial monographs in the future.
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Meropenem-clavulanate: a new strategy for the treatment of tuberculosis?
TL;DR: The Great White Plague: Mycobacterium tuberculosis, the bacteria causing tuberculosis, is a continuing threat to global health through the emergence of resistant strains and the lack of novel therapeutic agents.
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Impurity profile of amino acids
Susanne Kopec,Ulrike Holzgrabe +1 more
- 01 Aug 2005
TL;DR: Information is urgently needed about the production processes and the related impurity profile of Amino acids to replace the non-selective and non-sensitive TLC test with chromatographic or electrophoretic methods limiting the impurities to 0.1 per cent.
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