Ulrich Schüller
University of Hamburg
274 Papers
590 Citations
Ulrich Schüller is an academic researcher from University of Hamburg. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 47, co-authored 188 publications. Previous affiliations of Ulrich Schüller include University of Bonn & German Cancer Research Center.
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Papers
Outcome in unresectable glioblastoma: MGMT promoter methylation makes the difference
Niklas Thon,Jun Thorsteinsdottir,Sabina Eigenbrod,Ulrich Schüller,Ulrich Schüller,Jürgen Lutz,Simone Kreth,Claus Belka,Jörg-Christian Tonn,Maximilian Niyazi,Friedrich W. Kreth +10 more
TL;DR: Methylation of the MGMT promoter was the strongest favorable predictor for overall survival, and was also associated with higher frequencies of treatment response and prolonged post-recurrence survival, in patients undergoing upfront radiotherapy plus concomitant and maintenance temozolomide.
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Molecular profiling of an osseous metastasis in glioblastoma during checkpoint inhibition: potential mechanisms of immune escape
Malte Mohme,Cecile L. Maire,Simon Schliffke,Simon A. Joosse,Malik Alawi,Jakob Matschke,Ulrich Schüller,Judith Dierlamm,Tobias Martens,Klaus Pantel,Sabine Riethdorf,Katrin Lamszus,Manfred Westphal +12 more
TL;DR: The study highlights the fact that despite an effective control of intracranial GBM, certain tumour clones have the ability to evade the tumour-specific T-cell response and cause progression even outside of the CNS.
Grating-based X-ray phase-contrast tomography of atherosclerotic plaque at high photon energies
Holger Hetterich,Sandra Fill,Julia Herzen,Marian Willner,Irene Zanette,Irene Zanette,Timm Weitkamp,Alexander Rack,Ulrich Schüller,Mojtaba Sadeghi,Richard Brandl,Silvia Adam-Neumair,Maximilian F. Reiser,Franz Pfeiffer,Fabian Bamberg,Tobias Saam +15 more
TL;DR: PC-CT of atherosclerosis is feasible at high, clinically relevant photon energies and provides detailed information about plaque structure including features of high risk vulnerable plaques.
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Immunologic Profiling of Mutational and Transcriptional Subgroups in Pediatric and Adult High-Grade Gliomas.
Michael Bockmayr,Frederick Klauschen,Cecile L. Maire,Stefan Rutkowski,Manfred Westphal,Katrin Lamszus,Ulrich Schüller,Malte Mohme +7 more
TL;DR: This study shows that transcriptional and mutational subgroups are characterized by distinct immunologic tumor microenvironments, demonstrating the immunologic heterogeneity within high-grade gliomas and suggesting an immune-specific stratification for upcoming immunotherapy trials.
Newly Diagnosed Metastatic Intracranial Ependymoma in Children: Frequency, Molecular Characteristics, Treatment, and Outcome in the Prospective HIT Series
Martin Benesch,Martin Mynarek,Hendrik Witt,Hendrik Witt,Monika Warmuth-Metz,Torsten Pietsch,Brigitte Bison,Stefan M. Pfister,Stefan M. Pfister,Kristian W. Pajtler,Kristian W. Pajtler,Marcel Kool,Ulrich Schüller,Klaus Pietschmann,Björn-Ole Juhnke,Stephan Tippelt,Gudrun Fleischhack,Irene Schmid,Christof M. Kramm,Peter Vorwerk,Andreas Beilken,Carl Friedrich Classen,Pablo Hernáiz Driever,Gabriele Kropshofer,Thomas Imschweiler,Andreas Lemmer,Rolf-Dieter Kortmann,Stefan Rutkowski,Katja von Hoff,Katja von Hoff +29 more
TL;DR: Primary metastatic disease is rare in children with intracranial ependymoma with a frequency of 2.4% in this population-based, well-characterized cohort.
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