Ulla-Maja Bailey
University of Glasgow
8 Papers
2 Citations
Ulla-Maja Bailey is an academic researcher from University of Glasgow. The author has contributed to research in topics: DNA repair & PARP inhibitor. The author has an hindex of 3, co-authored 6 publications.
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Papers
Genomic analyses identify molecular subtypes of pancreatic cancer
Peter Bailey,David K. Chang,Katia Nones,Katia Nones,Amber L. Johns,Ann-Marie Patch,Ann-Marie Patch,Marie-Claude Gingras,David Miller,David Miller,Angelika N. Christ,Timothy J. C. Bruxner,Michael C.J. Quinn,Michael C.J. Quinn,Craig Nourse,Craig Nourse,Murtaugh Lc,Ivon Harliwong,Senel Idrisoglu,Suzanne Manning,Ehsan Nourbakhsh,Shivangi Wani,Shivangi Wani,J. Lynn Fink,Oliver Holmes,Oliver Holmes,Chin,Matthew J. Anderson,Stephen H. Kazakoff,Stephen H. Kazakoff,Conrad Leonard,Conrad Leonard,Felicity Newell,Nicola Waddell,Scott Wood,Scott Wood,Qinying Xu,Qinying Xu,Peter J. Wilson,Nicole Cloonan,Nicole Cloonan,Karin S. Kassahn,Karin S. Kassahn,Karin S. Kassahn,Darrin Taylor,Kelly Quek,Alan J. Robertson,Lorena Pantano,Laura Mincarelli,Luis Navarro Sanchez,Lisa Evers,Jianmin Wu,Mark Pinese,Mark J. Cowley,Jones,Jones,Emily K. Colvin,Adnan Nagrial,Emily S. Humphrey,Lorraine A. Chantrill,Lorraine A. Chantrill,Amanda Mawson,Jeremy L. Humphris,Angela Chou,Angela Chou,Marina Pajic,Marina Pajic,Christopher J. Scarlett,Christopher J. Scarlett,Andreia V. Pinho,Marc Giry-Laterriere,Ilse Rooman,Jaswinder S. Samra,James G. Kench,James G. Kench,James G. Kench,Jessica A. Lovell,Neil D. Merrett,Christopher W. Toon,Krishna Epari,Nam Q. Nguyen,Andrew Barbour,Nikolajs Zeps,Kim Moran-Jones,Nigel B. Jamieson,Janet Graham,Janet Graham,Fraser Duthie,Karin A. Oien,Karin A. Oien,Hair J,Robert Grützmann,Anirban Maitra,Christine A. Iacobuzio-Donahue,Christopher L. Wolfgang,Richard A. Morgan,Rita T. Lawlor,Corbo,Claudio Bassi,Borislav Rusev,Paola Capelli,Roberto Salvia,Giampaolo Tortora,Debabrata Mukhopadhyay,Gloria M. Petersen,Munzy Dm,William E. Fisher,Saadia A. Karim,Eshleman,Ralph H. Hruban,Christian Pilarsky,Jennifer P. Morton,Owen J. Sansom,Aldo Scarpa,Elizabeth A. Musgrove,Ulla-Maja Bailey,Oliver Hofmann,Oliver Hofmann,R. L. Sutherland,David A. Wheeler,Anthony J. Gill,Anthony J. Gill,Richard A. Gibbs,John V. Pearson,John V. Pearson,Andrew V. Biankin,Sean M. Grimmond,Sean M. Grimmond,Sean M. Grimmond +128 more
TL;DR: Detailed genomic analysis of 456 pancreatic ductal adenocarcinomas identified 32 recurrently mutated genes that aggregate into 10 pathways: KRAS, TGF-β, WNT, NOTCH, ROBO/SLIT signalling, G1/S transition, SWI-SNF, chromatin modification, DNA repair and RNA processing.
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Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer
Stephan Dreyer,Rosie Upstill-Goddard,Viola Paulus-Hock,Clara Paris,Eirini Lampraki,Eloise Dray,Bryan Serrels,Giuseppina Caligiuri,Selma Rebus,Dennis Plenker,Zachary C. Galluzzo,Holly Brunton,Richard Cunningham,Mathias Tesson,Craig Nourse,Ulla-Maja Bailey,D. Marc Jones,Kim Moran-Jones,Derek W. Wright,Fraser Duthie,Karin A. Oien,Lisa Evers,Colin J. McKay,Grant A. McGregor,Aditi Gulati,Rachel Brough,Ilirjana Bajrami,Stephan Pettitt,Michele L. Dziubinski,Juliana Candido,Frances R. Balkwill,Simon T. Barry,Robert Grützmann,Lola Rahib,Amber L. Johns,Marina Pajic,Fieke E. M. Froeling,Phillip Beer,Elizabeth A. Musgrove,Gloria M. Petersen,Alan Ashworth,Margaret C. Frame,Howard C. Crawford,Diane M. Simeone,Christopher J. Lord,Debabrata Mukhopadhyay,Christian Pilarsky,David A. Tuveson,Susanna L. Cooke,Nigel B. Jamieson,Jennifer P. Morton,Owen J. Sansom,Peter Bailey,Andrew V. Biankin,David K. Chang +54 more
TL;DR: Replication stress and DDR deficiency are independent of each other, creating opportunities for therapy in DDR-proficient PC and after platinum therapy.
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Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer
Stephan Dreyer,Stephan Dreyer,Rosie Upstill-Goddard,Viola Paulus-Hock,Clara Paris,Eirini-Maria Lampraki,Eloise Dray,Bryan Serrels,Bryan Serrels,Giuseppina Caligiuri,Selma Rebus,Holly Brunton,Richard Cunningham,Craig Nourse,Ulla-Maja Bailey,D. Marc Jones,Kim Moran-Jones,Derek W. Wright,Fraser Duthie,Karin A. Oien,Lisa Evers,Colin J. McKay,Colin J. McKay,Grant A. McGregor,Aditi Gulati,Rachel Brough,Ilirjana Bajrami,Stephan Pettitt,Michele L. Dziubinski,Juliana Candido,Frances R. Balkwill,Simon T. Barry,Robert Grützmann,Lola Rahib,Amber L. Johns,Marina Pajic,Fieke E. M. Froeling,Fieke E. M. Froeling,Phillip Beer,Elizabeth A. Musgrove,Gloria M. Petersen,Alan Ashworth,Alan Ashworth,Margaret C. Frame,Howard C. Crawford,Diane M. Simeone,Christopher J. Lord,Debabrata Mukhopadhyay,Christian Pilarsky,Susanna L. Cooke,Nigel B. Jamieson,Nigel B. Jamieson,Jennifer P. Morton,Owen J. Sansom,Owen J. Sansom,Peter Bailey,Andrew V. Biankin,Andrew V. Biankin,Andrew V. Biankin,David K. Chang,David K. Chang,David K. Chang +61 more
TL;DR: It is shown that patient-derived cell lines faithfully recapitulate the epithelial component of pancreatic tumors including previously described molecular subtypes and generates a novel signature of replication stress with potential clinical utility in predicting response to ATR and WEE1 inhibitor treatment.
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Driver gene combinations dictate cutaneous squamous cell carcinoma disease continuum progression
P. Bailey,Rachel A. Ridgway,Patrizia Cammareri,M. Treanor-Taylor,Ulla-Maja Bailey,C. Schoenherr,Max Bone,Daniel Schreyer,K. Purdie,Jason Thomson,W. Rickaby,Rene Jackstadt,Andrew D. Campbell,Emmanouil Dimonitsas,Alexander J. Stratigos,Sarah T. Arron,Jun Wang,Karen Blyth,Charlotte M. Proby,Catherine A. Harwood,Owen J. Sansom,Irene M. Leigh,Gareth J. Inman +22 more
TL;DR: Comparative systems analysis of human cSCC coupled with the generation of genetically engineered murine models reveal that combinatorial sequential inactivation of the tumour suppressor genes Tgfbr2, Trp53, and Notch1 coupled with activation of Ras signalling progressively drives cS CC progression along a differentiated to progenitor axis.
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Using Chromatin Accessibility to Delineate Therapeutic Subtypes in Pancreatic Cancer Patient-Derived Cell Lines.
Holly Brunton,Ian M. Garner,Ulla-Maja Bailey,Rosie Upstill-Goddard,Peter Bailey,Peter Bailey +5 more
- 04 Aug 2020
TL;DR: A revised ATAC-seq protocol to study chromatin accessibility in adherent patient-derived cell lines is presented and details on how to calculate the library molarity using Agilent’s Bioanalyzer and an analysis pipeline for peak calling and transcription factor mapping are provided.
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