Ulla Döhnert
University of Lübeck
6 Papers
38 Citations
Ulla Döhnert is an academic researcher from University of Lübeck. The author has contributed to research in topics: Disorders of sex development & Testosterone. The author has an hindex of 5, co-authored 6 publications.
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Papers
Management of disorders of sex development
Olaf Hiort,Wiebke Birnbaum,Louise Marshall,Lutz Wünsch,Ralf Werner,Tatjana Schröder,Ulla Döhnert,Paul-Martin Holterhus +7 more
TL;DR: The inclusion of trained peer support in the multidisciplinary DSD team seems to be integral to the supportive management of patients with DSDs, which requires acceptance of the fact that deviation from the traditional definitions of gender is not necessarily pathologic.
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Gonadectomy in Complete Androgen Insensitivity Syndrome: Why and When?
TL;DR: For women with CAIS who wish to keep their gonads, a biannual screening program which has to be evaluated in a prospective multi-center trial is proposed.
Testosterone Synthesis in Patients with 17β-Hydroxysteroid Dehydrogenase 3 Deficiency
Ralf Werner,Alexandra Kulle,I. Sommerfeld,Felix G. Riepe,Stefan A. Wudy,Michaela F. Hartmann,H. Merz,Ulla Döhnert,Silvano Bertelloni,Paul-Martin Holterhus,Olaf Hiort +10 more
TL;DR: In 17β-HSD 3 deficiency, relevant amounts of testosterone are synthesized most probably through AKR1C3 in the testis and not peripherally in GSF, and under testis-equivalent androstenedione concentration, testosterone can be synthesized in 17 β- HSD 3-negative GSF.
Novel Insights into 46,XY Disorders of Sex Development due to NR5A1 Gene Mutation
Ralf Werner,Isabel Mönig,Julia August,Clemens Freiberg,Ralf Lünstedt,Benedikt Reiz,Lutz Wünsch,Paul-Martin Holterhus,Alexandra Kulle,Ulla Döhnert,Stefan A. Wudy,Annette Richter-Unruh,Christoph Thorns,Olaf Hiort +13 more
TL;DR: This case demonstrates that the current classification of 46,XY disorders of sex development should be updated to encompass the overlapping phenotypes of some genetic conditions within 46, XY DSD and concludes that the NR5A1 p.L230R mutation most likely leads to a spatial and time-dependent Leydig cell and Sertoli cell dysfunction during development not causing the classical gonadal dysgenesis phenotype.
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Assessing the health-related management of people with differences of sex development.
Martina Jürgensen,Marion Rapp,Ulla Döhnert,Fabian-Simon Frielitz,Faisal Ahmed,Faisal Ahmed,Martine Cools,Ute Thyen,Olaf Hiort +8 more
TL;DR: In this paper, the authors summarize the social and legal approach to care for DSD during the last two decades and report the main results of European research activities, and briefly review the results of recently funded European research projects dealing with health-related issues in DSD like EU COST Action DSD, I-DSD, and dsd-LIFE, and address the compilation of quality indicators that will be needed to benchmark health care provision and health care-related outcomes.
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