Uli Binder
Technische Universität München
19 Papers
78 Citations
Uli Binder is an academic researcher from Technische Universität München. The author has contributed to research in topics: Chemistry & PEGylation. The author has an hindex of 8, co-authored 15 publications.
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Papers
Consistent success in life-supporting porcine cardiac xenotransplantation
Matthias Längin,Tanja Mayr,Bruno Reichart,Sebastian Michel,Stefan Buchholz,Sonja Guethoff,Alexey Dashkevich,Andrea Baehr,Stefanie Egerer,Andreas Bauer,Maks Mihalj,Alessandro Panelli,Lara Issl,Jiawei Ying,Ann Kathrin Fresch,Ines Buttgereit,Maren Mokelke,Julia Radan,Fabian Werner,I. Lutzmann,Stig Steen,Trygve Sjöberg,Audrius Paskevicius,Liao Qiuming,Riccardo Sfriso,Robert Rieben,Maik Dahlhoff,Barbara Kessler,Elisabeth Kemter,Mayuko Kurome,Valeri Zakhartchenko,Katharina Klett,Katharina Klett,Rabea Hinkel,Rabea Hinkel,Christian Kupatt,Almuth Falkenau,Simone Reu,Reinhard Ellgass,Rudolf Herzog,Uli Binder,Günter Wich,Arne Skerra,David Ayares,Alexander Kind,Uwe Schönmann,Franz-Josef Kaup,Christian Hagl,Eckhard Wolf,Nikolai Klymiuk,Paolo Brenner,Jan-Michael Abicht +51 more
TL;DR: It is shown that α1,3-galactosyltransferase-knockout pig hearts that express human CD46 and thrombomodulin require non-ischaemic preservation with continuous perfusion and post-transplantation growth control to ensure long-term orthotopic function of the xenograft in baboons, the most stringent preclinical xenotransplantation model.
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PASylation: a biological alternative to PEGylation for extending the plasma half-life of pharmaceutically active proteins
Martin Schlapschy,Uli Binder,Claudia Börger,Ina Theobald,Klaus Wachinger,Sigrid Kisling,Dirk Haller,Arne Skerra +7 more
TL;DR: It is demonstrated that PASylation bestows typical biologics, such as interferon, growth hormone or Fab fragments, with considerably prolonged circulation and boosts bioactivity in vivo.
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High-throughput sorting of an Anticalin library via EspP-mediated functional display on the Escherichia coli cell surface.
TL;DR: The EspP autotransporter-mediated E. coli surface display in combination with high-throughput fluorescence-activated cell sorting (FACS) provides an efficient strategy to select for Anticalins, and possibly other small protein scaffolds, with improved binding properties, which is particularly useful for in vitro affinity maturation but may also serve for the selection of novel target specificity from naive libraries.
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Endoplasmic Reticulum Stress Response Promotes Cytotoxic Phenotype of CD8αβ+ Intraepithelial Lymphocytes in a Mouse Model for Crohn’s Disease-like Ileitis
Jung-Su Chang,Soeren Ocvirk,Emanuel Berger,Sigrid Kisling,Uli Binder,Arne Skerra,Amy S. Lee,Dirk Haller +7 more
TL;DR: ER stress-associated UPR mechanisms promote the development and maintenance of the pathogenic cytotoxic CD8αβ+ IEL phenotype in the mouse model of Crohn’s disease-like ileitis.
Patent
Biosynthetic proline/alanine random coil polypeptides and their uses
Arne Skerra,Uli Binder,Martin Schlapschy +2 more
- 20 May 2011
TL;DR: In this article, the use and methods of use of a biosynthetic random coil polypeptide (RCLP) segment or a conjugate are described. And the uses of these conjugates include medical uses, diagnostic uses or uses in the food industry as well as other industrial applications, like in the paper industry, in oil recovery, etc.
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