Ulf de Faire

TL;DR: In this article, the authors identified 66 blood pressure-associated loci, of which 17 were new; 15 harbored multiple distinct association signals, and 66 index SNPs were enriched for cis-regulatory elements, particularly in vascular endothelial cells, consistent with a primary role in blood pressure control through modulation of vascular tone across multiple tissues.

TL;DR: The main projects within which the new collections of both biological samples as well as phenotypic measures have been collected are described and coverage by year of birth, zygosity determination, ethnic heterogeneity, and influences of in vitro fertilization are described.

TL;DR: A meta-analysis of 22 genome-wide association studies in 38,968 women of European descent identified 13 loci newly associated with age at natural menopause, including genes implicated in DNA repair, immune function and immune function.

TL;DR: Overall, a majority of the plasma proteins studied showed evidence of regulation at the genetic level, enabling future studies of the causal architecture of human disease, which should aid discovery of new drug targets.