Ulf B. Göbel
Charité
162 Papers
2K Citations
Ulf B. Göbel is an academic researcher from Charité. The author has contributed to research in topics: Biology & Campylobacter jejuni. The author has an hindex of 56, co-authored 162 publications. Previous affiliations of Ulf B. Göbel include University of Freiburg & Humboldt University of Berlin.
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Papers
Determination of microbial diversity in environmental samples: pitfalls of PCR‐based rRNA analysis
TL;DR: Specific aspects of sample collection, cell lysis, nucleic acid extraction, PCR amplification, separation of amplified DNA, application of nucleic probes and data analysis are covered.
2.2K
Fluorescence in situ hybridization (FISH) for direct visualization of microorganisms.
Annette Moter,Ulf B. Göbel +1 more
TL;DR: In this review, methodological aspects, as well as problems and pitfalls of FISH are discussed in an examination of past, present and future applications.
840
Gram-Negative Bacteria Aggravate Murine Small Intestinal Th1-Type Immunopathology following Oral Infection with Toxoplasma gondii
Markus M. Heimesaat,Stefan Bereswill,André Fischer,David Fuchs,Daniela Struck,Julia Niebergall,Hannah-Katharina Jahn,Ildiko R. Dunay,Annette Moter,Dorothee Maria Gescher,Ralf R. Schumann,Ulf B. Göbel,Oliver Liesenfeld +12 more
TL;DR: Gram-negative bacteria, i.e., E. coli, aggravate pathogen-induced intestinal Th1-type immunopathology and may prove useful to study bacteria-host interactions in small intestinal inflammation and to test novel therapies based on modulation of gut flora.
Anti-inflammatory effects of resveratrol, curcumin and simvastatin in acute small intestinal inflammation
Stefan Bereswill,Melba Muñoz,André Fischer,Rita Plickert,Lea-Maxie Haag,Bettina Otto,Anja A. Kühl,Christoph Loddenkemper,Ulf B. Göbel,Markus M. Heimesaat +9 more
TL;DR: Oral treatment with Resveratrol, Curcumin or Simvastatin ameliorates acute small intestinal inflammation by down-regulating Th1-type immune responses and prevents bacterial translocation by maintaining gut barrier function.
Naturally occurring anti–IFN-γ autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans
Conny Höflich,Robert Sabat,Simone Rosseau,Bettina Temmesfeld,Hortense Slevogt,Wolf-Dietrich Döcke,Gerald Grütz,Christian Meisel,Elke Halle,Ulf B. Göbel,Hans-Dieter Volk,Norbert Suttorp +11 more
TL;DR: Screening for neutralizing anti-IFN-Gamma autoantibodies should supplement testing for IFN-gamma and IL-12 pathway defects in patients with recurrent infections with intracellular pathogens, especially with nontuberculous mycobacteria.
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