Tuuli Mustonen
University of Helsinki
5 Papers
10 Citations
Tuuli Mustonen is an academic researcher from University of Helsinki. The author has contributed to research in topics: Amyloidosis & Haplotype. The author has an hindex of 4, co-authored 5 publications.
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Papers
Cardiac manifestations in Finnish gelsolin amyloidosis patients
Tuuli Mustonen,Arttu Holkeri,Miia Holmström,Sari Atula,Sami Pakarinen,Lauri Lehmonen,Sari Kiuru-Enari,Aapo L. Aro +7 more
TL;DR: Electrocardiographic findings in AGel amyloidosis and their relation to cardiac magnetic resonance (CMR) changes are focused on, explaining conduction disorders, although pacemaker therapy is rarely required.
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Common origin of the gelsolin gene variant in 62 Finnish AGel amyloidosis families.
TL;DR: Results provide strong evidence that although there is a known mutational hot spot at GSN c.640G, all of the studied 62 Finnish AGel amyloidosis families are genetically linked to a common ancestor.
Myocardial tissue characterization in patients with hereditary gelsolin (AGel) amyloidosis using novel cardiovascular magnetic resonance techniques
TL;DR: Myocardial involvement in AGel amyloidosis is significant, but the effects are local, focusing on the basal plane of the LV, and volumetry, myocardial feature-tracking strain, rotation, torsion, native T1, ECV, and LGE were investigated.
Hearing problems in patients with hereditary gelsolin amyloidosis.
TL;DR: In this paper, a clinical study consisting of the Speech, Spatial and Qualities of Hearing Scale (SSQ) questionnaire, clinical examination, automated pure-tone audiometry and a speech-in-noise test was designed.
Finnish gelsolin amyloidosis causes significant disease burden but does not affect survival : FIN-GAR phase II study
TL;DR: The finding that AGel amyloidosis does not shorten the life span of the patients at least for the first 75 years is explained in part by the finding that severe renal and cardiac manifestations are rare as compared to other systemicAmyloidoses.