Tuula Tolvanen
Turku University Hospital
66 Papers
244 Citations
Tuula Tolvanen is an academic researcher from Turku University Hospital. The author has contributed to research in topics: Medicine & Positron emission tomography. The author has an hindex of 19, co-authored 54 publications. Previous affiliations of Tuula Tolvanen include University of Turku.
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Papers
In Vivo Imaging of Prostate Cancer Using [68Ga]-Labeled Bombesin Analog BAY86-7548
Esa Kähkönen,Ivan Jambor,Jukka Kemppainen,Kaisa Lehtiö,Tove J. Grönroos,Anna Kuisma,Pauliina Luoto,H. Sipilä,Tuula Tolvanen,Kalle Alanen,Jonna Silén,Markku Kallajoki,Anne Roivainen,Niklaus Schäfer,Roger Schibli,Martina Dragic,Anass Johayem,Ray Valencia,Sandra Borkowski,Heikki Minn +19 more
TL;DR: BAY86-7548 PET/CT is a promising molecular imaging technique for detecting intraprostatic prostate cancer and has a sensitivity, specificity, and accuracy of 88, 81, and 83%, respectively, for detection of primary PCa and sensitivity for metastatic lymph nodes using histology as gold standard.
200
Human brown adipose tissue [15O]O2 PET imaging in the presence and absence of cold stimulus
Mueez U Din,Mueez U Din,Juho Raiko,Juho Raiko,Teemu Saari,Teemu Saari,Nobu Kudomi,Tuula Tolvanen,Tuula Tolvanen,Vesa Oikonen,Vesa Oikonen,Jarmo Teuho,Jarmo Teuho,Hannu Sipilä,Hannu Sipilä,Nina Savisto,Nina Savisto,Riitta Parkkola,Pirjo Nuutila,Pirjo Nuutila,Kirsi A. Virtanen,Kirsi A. Virtanen +21 more
TL;DR: This study suggests that BAT is a minor and deep muscles are a major contributor to CIT, and BAT-specific EE associated with BAT blood flow and NEFA uptake both at RT and during cold stimulus.
Plasma Pharmacokinetics, Whole-Body Distribution, Metabolism, and Radiation Dosimetry of 68Ga Bombesin Antagonist BAY 86-7548 in Healthy Men
Anne Roivainen,Esa Kähkönen,Pauliina Luoto,Sandra Borkowski,Birte Hofmann,Ivan Jambor,Kaisa Lehtiö,Tuija Rantala,Antje Rottmann,H. Sipilä,Rick Sparks,Sami Suilamo,Tuula Tolvanen,Ray Valencia,Heikki Minn +14 more
TL;DR: Intravenously injected BAY 86-7548 is safe, and rapid metabolism is demonstrated, and the organs with the highest absorbed doses were the urinary bladder wall and the pancreas.
104
•Journal Article
68Ga-Labeled Oligonucleotides for In Vivo Imaging with PET
Anne Roivainen,Tuula Tolvanen,Satu Salomäki,Gabor Lendvai,Irina Velikyan,Petri Numminen,Maria Välilä,Hannu Sipilä,Mats Bergström,Pirkko Härkönen,Harri Lönnberg,Bengt Långström +11 more
TL;DR: It is concluded that (68)Ga labeling of oligonucleotides is a convenient approach for in vivo imaging and quantification of olig onucleotide biokinetics in living animals with PET.
103
•Journal Article
Biodistribution and Radiation Dosimetry of the Amyloid Imaging Agent 11C-PIB in Humans
Noora M. Scheinin,Tuula Tolvanen,Ian Andrew Wilson,Eveliina Arponen,Kjell Någren,Juha O. Rinne +5 more
TL;DR: The established clinical dose of (11)C-PIB required for 3-dimensional PET amyloid imaging has an acceptable effective radiation dose and is comparable with the average exposure expected in other PET brain receptor tracer studies.
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