Trung N. Tran
MedImmune
7 Papers
26 Citations
Trung N. Tran is an academic researcher from MedImmune. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 5, co-authored 7 publications.
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Papers
Can rheumatoid arthritis (RA) registries provide contextual safety data for modern RA clinical trials? The case for mortality and cardiovascular disease
Kaleb Michaud,Niklas Berglind,Stefan Franzén,Thomas Frisell,Christopher Garwood,Jeff Greenberg,Meilien Ho,Marie Holmqvist,Laura Horne,Eisuke Inoue,Fredrik Nyberg,Fredrik Nyberg,Dimitrios A Pappas,George W. Reed,Deborah P M Symmons,Eiichi Tanaka,Trung N. Tran,Suzanne M M Verstappen,Eveline Wesby-van Swaay,Hisashi Yamanaka,Johan Askling +20 more
TL;DR: This coordinated approach to contextualising RA RCT safety data demonstrated reasonable differences and consistency in rates for mortality and CVD across registries, and comparable RCT rates, and may serve as a model method to supplement clinical trial analyses for drug development programmes.
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Methodological challenges when comparing demographic and clinical characteristics of international observational registries.
Suzanne M M Verstappen,Johan Askling,Niklas Berglind,Stefan Franzén,Thomas Frisell,Christopher Garwood,Jeff Greenberg,Marie Holmqvist,Laura Horne,Kathy Lampl,Kaleb Michaud,Fredrik Nyberg,Dimitrios A. Pappas,George W. Reed,Deborah P M Symmons,Eiichi Tanaka,Trung N. Tran,Hisashi Yamanaka,Meilien Ho +18 more
TL;DR: Comparisons of data from different registries can be helpful in understanding variations in many aspects of rheumatoid arthritis (RA) and the comparability of demographic, clinical, and comorbidity data from 5 international RA registries is improved.
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Using epidemiological registry data to provide background rates as context for adverse events in a rheumatoid arthritis drug development program: A coordinated approach
Fredrik Nyberg,Fredrik Nyberg,Johan Askling,Johan Askling,Niklas Berglind,Stefan Franzén,Meilien Ho,Marie Holmqvist,Laura Horne,Kathy Lampl,Kaleb Michaud,Dimitrios A Pappas,George W. Reed,Deborah P M Symmons,Deborah P M Symmons,Eiichi Tanaka,Trung N. Tran,Suzanne M M Verstappen,Eveline Wesby-van Swaay,Hisashi Yamanaka,Jeff Greenberg +20 more
TL;DR: Methods to improve safety contextualization for a rheumatoid arthritis drug development program through coordinated analyses of multiple registries are developed.
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Incidence density of serious infection, opportunistic infection, and tuberculosis associated with biologic treatment in patients with rheumatoid arthritis - a systematic evaluation of the literature.
TL;DR: The data on serious infection may be used to evaluate the public health risk and benefit of biologic treatment and serve as a point of reference for future studies, and the limited data on opportunistic infection and the lack of a consistent definition of opportunism infection invite caution for a benchmark rate for opportunistic infections.
FRI0447 Epidemiology of idiopathic inflammatory myopathies in england – a database analysis
TL;DR: A higher IIM prevalence in England than previously reported in other countries is found and the prevalence was positively associated with female gender and older age.
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