Trevor N. Clark
Simon Fraser University
9 Papers
Trevor N. Clark is an academic researcher from Simon Fraser University. The author has contributed to research in topics: Medicine & Mass spectrometry. The author has an hindex of 2, co-authored 4 publications.
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Papers
The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery.
Jeffrey A. van Santen,Gregoire Jacob,Amrit Leen Singh,Victor Aniebok,Marcy J. Balunas,Derek Bunsko,Fausto Carnevale Neto,Fausto Carnevale Neto,Fausto Carnevale Neto,Laia Castano-Espriu,Chen Chang,Trevor N. Clark,Jessica C. Little,David A. Delgadillo,Pieter C. Dorrestein,Katherine R. Duncan,Joseph M. Egan,Melissa M. Galey,F. P. Jake Haeckl,Alex Hua,Alison H. Hughes,Dasha Iskakova,Aswad S Khadilkar,Jung-Ho Lee,Sanghoon Lee,Nicole LeGrow,Dennis Y. Liu,Jocelyn Macho,Catherine McCaughey,Marnix H. Medema,Ram P. Neupane,Timothy J. O’Donnell,Jasmine S. Paula,Laura M. Sanchez,Anam F. Shaikh,Sylvia Soldatou,Barbara R. Terlouw,Tuan Anh Tran,Tuan Anh Tran,Mercia C. Valentine,Justin J. J. van der Hooft,Duy A. Vo,Mingxun Wang,Darryl Wilson,Katherine E. Zink,Roger G. Linington +45 more
TL;DR: The Natural Products Atlas is designed as a community-supported resource to provide a central repository for known natural product structures from microorganisms and is the first comprehensive, open access resource of this type.
The Natural Products Atlas 2.0 : a database of microbially-derived natural products
Jeffrey A. van Santen,Ella F. Poynton,Dasha Iskakova,Emily McMann,Tyler A. Alsup,Trevor N. Clark,Claire H. Fergusson,David P. Fewer,Alison H. Hughes,Caitlin A. McCadden,Jonathan Parra,Sylvia Soldatou,Jeffrey D. Rudolf,Elisabeth M.-L. Janssen,Katherine R. Duncan,Roger G. Linington +15 more
TL;DR: The Natural Products Atlas (Npatlas) as discussed by the authors is a database of known microbial natural products structures, which includes a full RESTful application programming interface (API), a new website framework and an expanded database that includes 8128 new compounds.
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Annotation of natural product compound families using molecular networking topology and structural similarity fingerprinting
Nicholas J. Morehouse,Trevor N. Clark,Emily McMann,Jeffrey A. van Santen,F. P. Jake Haeckl,Christopher A. Gray,Roger G. Linington +6 more
TL;DR: The Structural similarity Network Annotation Platform for Mass Spectrometry (SNAP-MS) as discussed by the authors matches chemical similarity grouping in the Natural Products Atlas to grouping of mass spectrometry features from molecular networking.
Evaluation of Ion Mobility Spectrometry for Improving Constitutional Assignment in Natural Product Mixtures.
TL;DR: In this article , the authors examined the effect of integrating ion mobility spectrometry (IMS) to the liquid chromatography-coupled high-resolution tandem mass spectrometers (MS/MS or MS2) for the characterization of natural product mixtures.
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High-Throughput Functional Annotation of Natural Products by Integrated Activity Profiling
Suzie K. Hight,Kenji L. Kurita,Elizabeth A. McMillan,Walter M. Bray,Trevor N. Clark,Anam F. Shaikh,F. P. Jake Haeckl,Fausto Carnevale-Neto,Scott La,Akshar Lohith,Rachel M. Vaden,Jeon Lee,Shuguang Wei,R. Scott Lokey,Michael A. White,Roger G. Linington,John B. MacMillan,John B. MacMillan +17 more
TL;DR: A comprehensive platform that uses Similarity Network Fusion (SNF) to improve MOA predictions by integrating data from the cytological profiling high-content imaging platform and the gene expression platform FUSION is reported.