Trace E. Tessier
7 Papers
40 Citations
Trace E. Tessier is an academic researcher. The author has contributed to research in topics: Relaxometry & Magnetic nanoparticles. The author has an hindex of 7, co-authored 7 publications.
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Papers
Detection of breast cancer cells using targeted magnetic nanoparticles and ultra-sensitive magnetic field sensors
Helen J. Hathaway,Kimberly S. Butler,Natalie L. Adolphi,Debbie M. Lovato,Robert Belfon,Danielle L. Fegan,Todd C. Monson,Jason E Trujillo,Trace E. Tessier,H.C. Bryant,Dale L. Huber,Richard S. Larson,Edward R. Flynn +12 more
TL;DR: The results suggest that the antibody-conjugated magnetic nanoparticles are promising reagents to apply to in vivo breast tumor cell detection, and that SQUID-detected magnetic relaxometry is a viable, rapid, and highly sensitive method for in vitro nanoparticle development and eventual in vivo tumor detection.
Imaging of Her2-targeted magnetic nanoparticles for breast cancer detection: comparison of SQUID-detected magnetic relaxometry and MRI.
Natalie L. Adolphi,Kimberly S. Butler,Debbie M. Lovato,Trace E. Tessier,Jason E Trujillo,Helen J. Hathaway,Danielle L. Fegan,Todd C. Monson,Tyler E. Stevens,Dale L. Huber,Jaivijay Ramu,Michelle L. Milne,Stephen A. Altobelli,H.C. Bryant,Richard S. Larson,Edward R. Flynn +15 more
TL;DR: The potential of SQUID-detected magnetic relaxometry imaging for the specific detection of breast cancer and the monitoring of magnetic nanoparticle-based therapies is demonstrated.
Enhanced leukemia cell detection using a novel magnetic needle and nanoparticles
Jason E. Jaetao,Kimberly S. Butler,Natalie L. Adolphi,Debbie M. Lovato,H.C. Bryant,Ian Rabinowitz,Stuart S. Winter,Trace E. Tessier,Helen J. Hathaway,Christian Bergemann,Edward R. Flynn,Richard S. Larson +11 more
TL;DR: It is suggested that bone marrow biopsy using antigen-targeted magnetic nanoparticles and a magnetic needle for the evaluation of minimal residual disease in CD34-positive acute leukemias can significantly enhance sensitivity compared with the current standard of care.
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Characterization of magnetite nanoparticles for SQUID-relaxometry and magnetic needle biopsy
Natalie L. Adolphi,Dale L. Huber,Jason E. Jaetao,H.C. Bryant,Debbie M. Lovato,Danielle L. Fegan,Eugene L. Venturini,Todd C. Monson,Trace E. Tessier,Helen J. Hathaway,Christian Bergemann,Richard S. Larson,Edward R. Flynn +12 more
TL;DR: Analysis of the binding of CD34-conjugated nanoparticles to U937 leukemia cells revealed 60,000 nanoparticles per cell, which were collected from whole blood using a prototype magnetic biopsy needle, with a capture efficiency of >65% from a 750 µl sample volume in 1 minute.
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Magnetic properties of nanoparticles useful for SQUID relaxometry in biomedical applications
H.C. Bryant,Natalie L. Adolphi,Dale L. Huber,Danielle L. Fegan,Todd C. Monson,Trace E. Tessier,Edward R. Flynn +6 more
TL;DR: Using dynamic susceptometry measurements to extract semiempirical temperature-dependent, 255 to 400 K, magnetic parameters that determine the behavior of single-core nanoparticles useful for SQUID relaxometry in biomedical applications, it is found that SQUIDs relaxation and excitation curves on the same sample are well described.
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