Toshiya Misawa
Nagoya University
9 Papers
111 Citations
Toshiya Misawa is an academic researcher from Nagoya University. The author has contributed to research in topics: Cell culture & Messenger RNA. The author has an hindex of 5, co-authored 8 publications.
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Papers
α-Fetoprotein in malignant germ cell tumors of the ovary
Michiyasu Kawai,Yoshihito Furuhashi,Kano T,Toshiya Misawa,Nobuo Nakashima,Sen-ei Hattori,Yoshie Okamoto,Iwao Kobayashi,Ohta M,Yoshitaro Arii,Yutaka Tomoda +10 more
TL;DR: It was found that AFP levels should be monitored closely for at least 1 year after induction of remission and an increase in the AFP to a positive level, even without clinical signs of recurrence, should be regarded as a recurrence.
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Establishment and characterization of acquired resistance to platinum anticancer drugs in human ovarian carcinoma cells.
Toshiya Misawa,Fumitaka Kikkawa,Osamu Maeda,Naoko H. Obata,Koji Higashide,Nobuhiko Suganuma,Yutaka Tomoda +6 more
TL;DR: In this paper, the authors investigated differences in resistance to cis-diamminedichloroplatinum (II) and diammine (1,1-cyclobutanecarboxylato)platinum(II) (CBDCA), and their newly developed derivative, ((-)-(R)-2-aminomethylpyrrolidine (1.1)-cyclobutanedicarboxymethylato (DWA2114R), and established four types of resistant cell lines from a parental cell line (NOS2) of a
Growth inhibitory effect of bestatin on choriocarcinoma cell lines in vitro
Kazuhiko Ino,Setsuko Goto,Akemi Kosaki,Seiji Nomura,Eiko Asada,Toshiya Misawa,Yoshihito Furuhashi,Shigehiko Mizutani,Yutaka Tomoda +8 more
TL;DR: The results suggest that bestatin has not only an indirect host-mediated anti-tumor activity, but also a direct growth-inhibitory effect on some kinds of cancer cell lines.
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Mitomycin C cross-resistance induced by adriamycin in human ovarian cancer cells in vitro.
Kimio Mizuno,Yoshihito Furuhashi,Osamu Maeda,Mitsumasa Iwata,Toshiya Misawa,Michiyasu Kawai,Kano T,Yutaka Tomoda +7 more
TL;DR: The results strongly suggest that the resistance to mitomycin C observed in the Adriamycin-resistant cells was due to some other mechanism than that causing multidrug resistance.
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Accumulation of cis-Diamminedichloroplatinum (II) and Its Analogues in Sensitive and Resistant Human Ovarian Carcinoma Cells
Toshiya Misawa,Fumitaka Kikkawa,Hidenori Oguchi,Yoshimitsu Morikawa,Michiyasu Kawai,Osamu Maeda,Mitsumasa Iwata,Kano T,Yoshihito Furuhashi,Yutaka Tomoda +9 more
TL;DR: The studies indicate that the mechanisms of resistance to CDDP and analogues in NOS2CR cells are related in the main to reduced intracellular accumulation of drugs.
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