Toshiaki Takei
University of Tokyo
9 Papers
28 Citations
Toshiaki Takei is an academic researcher from University of Tokyo. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 4, co-authored 9 publications. Previous affiliations of Toshiaki Takei include Gakushuin University.
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Papers
Application of photoactive yellow protein as a photoresponsive module for controlling hemolytic activity of staphylococcal α-hemolysin.
Mihoko Ui,Yoshikazu Tanaka,Yasuyuki Araki,Takehiko Wada,Toshiaki Takei,Kouhei Tsumoto,Sumire Endo,Kazushi Kinbara +7 more
TL;DR: A chimeric protein (N-PYP-Hla), consisting of staphylococcal pore-forming toxin α-hemolysin and photoactive yellow protein, exhibited photoresponsive hemolytic activities, where visible light irradiation gave rise to retardation of hemolysis at 25 °C.
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Interleukin-6 sensitizes TNF-α and TRAIL/Apo2L dependent cell death through upregulation of death receptors in human cancer cells.
Emiko Sano,Akira Kazaana,Hisashi Tadakuma,Toshiaki Takei,Sodai Yoshimura,Yuya Hanashima,Yoshinari Ozawa,Atsuo Yoshino,Yutaka Suzuki,Takuya Ueda +9 more
TL;DR: In this article, the effects of IL-6 using SKBR3 cells were associated with the generation of apoptotic cells as analyzed by fluorescence microscopy and flow cytometry.
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Type 1 IFN inhibits the growth factor deprived apoptosis of cultured human aortic endothelial cells and protects the cells from chemically induced oxidative cytotoxicity
TL;DR: The results indicate that type 1 IFN, especially IFN‐β may be useful for the diseases with vascular endothelium damage such as atherosclerosis or restenosis after angioplasty as a medical treatment or a prophylactic.
6
Effects of Chain Length of an Amphipathic Polypeptide Carrying the Repeated Amino Acid Sequence (LETLAKA)n on α-Helix and Fibrous Assembly Formation
Toshiaki Takei,K. Hasegawa,Katsumi Imada,Keiichi Namba,Kouhei Tsumoto,Yukino Kuriki,Masakuni Yoshino,Kazumori Yazaki,Kazumori Yazaki,Shuichi Kojima,Tsunetomo Takei,Takuya Ueda,Kin-ichiro Miura,Kin-ichiro Miura +13 more
TL;DR: The results suggest that the formation of fibrous assemblies of amphipathic α-helices is due to the assembly of bundles via the hydrophobic faces of the helices and extension with hydrophilic noncovalent bonds containing a leucine.
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Production and characterization of genetically modified human IL-11 variants.
TL;DR: Results indicate N-terminal and M1 variants will be expected for practical use as potent agonists or antagonists of hIL-11.
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