16 Papers
Tonghui Xu is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Computer science & Biology. The author has an hindex of 11, co-authored 16 publications. Previous affiliations of Tonghui Xu include Nanchang University.
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Papers
High-throughput dual-colour precision imaging for brain-wide connectome with cytoarchitectonic landmarks at the cellular level
Hui Gong,Dongli Xu,Jing Yuan,Xiangning Li,Congdi Guo,Jie Peng,Yuxin Li,Lindsay A. Schwarz,Anan Li,Bihe Hu,Benyi Xiong,Qingtao Sun,Yalun Zhang,Jiepeng Liu,Qiuyuan Zhong,Tonghui Xu,Shaoqun Zeng,Qingming Luo +17 more
TL;DR: The results show that the simultaneous acquisition of labelled neural structures and cytoarchitecture reference in the same brain greatly facilitates precise tracing of long-range projections and accurate locating of nuclei.
Continuously tracing brain-wide long-distance axonal projections in mice at a one-micron voxel resolution.
Hui Gong,Shaoqun Zeng,Cheng Yan,Xiaohua Lv,Zhongqin Yang,Tonghui Xu,Zhao Feng,Wenxiang Ding,Xiaoli Qi,Anan Li,Jingpeng Wu,Qingming Luo +11 more
TL;DR: A whole-brain approach to systematically obtaining continuous neuronal pathways in a fluorescent protein transgenic mouse at a one-micron voxel resolution is described, believed to open an avenue to exploring both local and long-distance neural circuits that are related to brain functions and brain diseases down to the neurite level.
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Precise Cerebral Vascular Atlas in Stereotaxic Coordinates of Whole Mouse Brain.
Benyi Xiong,Anan Li,Yang Lou,Shangbin Chen,Ben Long,Jie Peng,Zhongqin Yang,Tonghui Xu,Xiaoquan Yang,Xiangning Li,Tao Jiang,Qingming Luo,Hui Gong +12 more
TL;DR: Reconstruction and statistical analysis of the microvascular network, including derivation of quantitative vascular densities, indicate significant differences mainly in vessels with diameters less than 8 μm and large than 20 μm across different brain regions.
Cell-Type-Specific Afferent Innervation of the Nucleus Accumbens Core and Shell
TL;DR: This work characterized the whole-brain and monosynaptic inputs to two main projection cell types – D1 dopamine receptor expressing medium spiny neurons (D1R-MSNs) and D2 dopamine receptorExpressing medium spines (D2R- MSNs) within the NAc core and NAc shell by rabies-mediated trans-synaptic tracing.
Skull optical clearing window for in vivo imaging of the mouse cortex at synaptic resolution.
TL;DR: A skull optical clearing window is introduced for imaging cortical structures at synaptic resolution and it is applied to study the plasticity of dendritic spines in critical periods and to visualize dendrites and microglia after laser ablation.