Tomoya Hirota
University of Tsukuba
38 Papers
145 Citations
Tomoya Hirota is an academic researcher from University of Tsukuba. The author has contributed to research in topics: Medicine & Rheumatoid arthritis. The author has an hindex of 13, co-authored 36 publications.
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Papers
The role of M3 muscarinic acetylcholine receptor reactive T cells in Sjögren's syndrome: A critical review
TL;DR: The findings indicate the crucial roles of M3R-reactive Th1 and Th17 cells in autoimmune sialadenitis, and suggest that these cells, in addition to anti-M3R antibodies, are potential targets in new treatments for SS.
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DNA microarray analysis of labial salivary glands in IgG4-related disease: comparison with Sjögren's syndrome.
Hiroto Tsuboi,Yuji Nakai,Mana Iizuka,Hiromitsu Asashima,Chihiro Hagiya,Sayaka Tsuzuki,Tomoya Hirota,Haruka Miki,Shinya Hagiwara,Yuya Kondo,Akihiko Tanaka,Masafumi Moriyama,Isao Matsumoto,Seiji Nakamura,Toshio Yoshihara,Keiko Abe,Takayuki Sumida +16 more
TL;DR: To compare gene expression in labial salivary glands from patients with IgG4‐related disease with that in LSGs from Patients with Sjögren's syndrome, a large number of genes from both groups are compared.
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A Crucial Role of RORγt in the Development of Spontaneous Sialadenitis-like Sjögren’s Syndrome
Mana Iizuka,Hiroto Tsuboi,Naomi Matsuo,Hiromitsu Asashima,Tomoya Hirota,Yuya Kondo,Yoichiro Iwakura,Satoru Takahashi,Isao Matsumoto,Takayuki Sumida +9 more
TL;DR: Results suggest that both RORγt-overexpressed CD4+ T cells and reduced Treg cells might contribute to the development of SS-like sialadenitis.
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Clinicopathological features of IgG4-related disease complicated with orbital involvement
Chihiro Hagiya,Hiroto Tsuboi,Masahiro Yokosawa,Shinya Hagiwara,Tomoya Hirota,Chinatsu Takai,Hiromitsu Asashima,Haruka Miki,Naoto Umeda,Masanobu Horikoshi,Yuya Kondo,Makoto Sugihara,Hiroshi Ogishima,Takeshi Suzuki,Takahiro Hiraoka,Yuichi Kaji,Isao Matsumoto,Tetsuro Oshika,Takayuki Sumida +18 more
TL;DR: The histopathological findings of orbital tissue match the characteristic features of IgG 4-RD, and Corticosteroid is effective for orbital and systemic involvement in IgG4-RD.
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Recurrent Kikuchi-Fujimoto Disease Successfully Treated by the Concomitant Use of Hydroxychloroquine and Corticosteroids.
Fumika Honda,Hiroto Tsuboi,Hirofumi Toko,Ayako Ohyama,Hidenori Takahashi,Saori Abe,Masahiro Yokosawa,Hiromitsu Asashima,Shinya Hagiwara,Tomoya Hirota,Yuya Kondo,Isao Matsumoto,Takayuki Sumida +12 more
TL;DR: This is the first case to suggest the effectiveness of HCQ for recurrent KFD in a Japanese patient and it is reported that hydroxychloroquine with low-dose PSL induced continuous remission.
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