Tomoko Ojima
Tokyo Medical and Dental University
9 Papers
113 Citations
Tomoko Ojima is an academic researcher from Tokyo Medical and Dental University. The author has contributed to research in topics: Human herpesvirus 6 & Viral load. The author has an hindex of 6, co-authored 9 publications.
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Papers
Use of real-time PCR to monitor human herpesvirus 6 reactivation after allogeneic bone marrow transplantation.
Junko H. Ohyashiki,A Suzuki,K Aritaki,A Nagate,N Shoji,K Ohyashiki,Tomoko Ojima,Kenji Abe,Kohtaro Yamamoto +8 more
TL;DR: This method of rapid quantification of HHV-6 genomes by the real-time PCR using a LightCycler may be useful not only to understand the reconstitution of the immune system following marrow transplantation but also to manage the care of patients.
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A rapid monitoring system of human herpesviruses reactivation by LightCycler in stem cell transplantation.
K Aritaki,Junko H. Ohyashiki,Junko H. Ohyashiki,Suzuki A,Tomoko Ojima,Kenji Abe,Norio Shimizu,Kohtaro Yamamoto,Kazuma Ohyashiki,Akinori Hoshika +9 more
TL;DR: The reactivation of β herpesviruses is associated with the occurrence of thrombotic microangiopathy (TMA) in two patients undergoing allogeneic BMT and may contribute in clarifying the pathological potential of human herpesvirus using a large number of clinical samples.
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Quantification of human herpesvirus 6 in healthy volunteers and patients with lymphoproliferative disorders by PCR-ELISA.
Junko H. Ohyashiki,Kenji Abe,Tomoko Ojima,Ping Wang,Chang Fang Zhou,Suzuki A,Kazuma Ohyashiki,Kohtaro Yamamoto +7 more
TL;DR: The results suggest that measurement of HHV-6 genomes using PCR-ELISA may be useful not only to understand the mechanism of HHv-6 infection in hemopoietic neoplasia but also to manage the care of immnocompromised patients such as bone marrow transplant patients.
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Efficient propagation of human herpesvirus 6B in a T-cell line derived from a patient with adult T-cell leukemia/lymphoma.
TL;DR: The results suggest that the activation of CD4+ T lymphocytes with mitogens such as PHA or IL‐2 and the expression of some cellular gene or the HTLV‐I gene might be essential for efficient propagation of HHV‐6B.
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IL-2-regulated persistent human herpesvirus-6B infection facilitates growth of adult T cell leukemia cells.
TL;DR: It is indicated that the HHV-6B-infected ATL cells stimulate the growth of the uninfected cells during persistent infection in culture, and cultures containing the infected cells grew significantly faster than the parental unin infected cells at the same concentration of IL-2.
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