Tomasz Powrózek
Medical University of Lublin
77 Papers
234 Citations
Tomasz Powrózek is an academic researcher from Medical University of Lublin. The author has contributed to research in topics: Lung cancer & Medicine. The author has an hindex of 14, co-authored 63 publications.
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Papers
Comparison of the effectiveness of erlotinib, gefitinib, and afatinib for treatment of non-small cell lung cancer in patients with common and rare EGFR gene mutations.
Paweł Krawczyk,Dariusz M. Kowalski,Rodryg Ramlau,Ewa Kalinka‑Warzocha,Kinga Winiarczyk,Katarzyna Stencel,Tomasz Powrózek,Katarzyna Reszka,Kamila Wojas Krawczyk,Maciej Bryl,Magdalena Wójcik‑Superczyńska,Maciej Głogowski,Aleksander Barinow Wojewódzki,Janusz Milanowski,Maciej Krzakowski +14 more
TL;DR: A retrospective analysis of 180 NSCLC patients with common and rare EGFR mutations treated with erlotinib, gefit inib, and afatinib showed similar efficacies based on treatment response, median PFS, and OS, suggesting that when undergoing EGFR-TKI treatment, patients with rare EG FR mutations showed similar OS but poorer PFS.
Plasma circulating microRNA-944 and microRNA-3662 as potential histologic type-specific early lung cancer biomarkers.
Tomasz Powrózek,Paweł Krawczyk,Dariusz M. Kowalski,Kinga Winiarczyk,Marta Olszyna-Serementa,Janusz Milanowski +5 more
TL;DR: The results suggest that the profile of studied miRNAs could be further evaluated and considered as potential lung cancer biomarkers and their lung tumor specificity in plasma samples of 90 patients with lung cancer and 85 healthy individuals using quantitative reverse transcription-polymerase chain reaction analysis.
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Methylation of the DCLK1 promoter region in circulating free DNA and its prognostic value in lung cancer patients.
Tomasz Powrózek,Paweł Krawczyk,Marcin Nicoś,Barbara Kuźnar-Kamińska,Halina Batura-Gabryel,Janusz Milanowski +5 more
TL;DR: The evaluation of DCLK1 promoter region methylation may be useful in both early diagnosis and prediction of the course of lung cancer.
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Evaluation of miR-506 and miR-4316 expression in early and non-invasive diagnosis of colorectal cancer
Paweł Krawczyk,Tomasz Powrózek,Tomasz Olesiński,Adam Dmitruk,Joanna Dziwota,Dariusz M. Kowalski,Janusz Milanowski +6 more
TL;DR: This study revealed that elevated expression of MiR-506 and miR-4316 in peripheral blood were potential molecular markers for early colorectal cancer.
The efficacy of EGFR gene mutation testing in various samples from non-small cell lung cancer patients: a multicenter retrospective study.
Paweł Krawczyk,Rodryg Ramlau,Joanna Chorostowska-Wynimko,Tomasz Powrózek,Marzena Anna Lewandowska,Janusz Limon,Bartosz Wasąg,Juliusz Pankowski,Jerzy Kozielski,Ewa Kalinka-Warzocha,Aleksandra Szczesna,Kamila Wojas-Krawczyk,Michal Skronski,Rafal Dziadziuszko,Paulina Jaguś,Ewelina Antoszewska,Justyna Szumiło,Bożena Jarosz,Aldona Woźniak,Wojciech Jóźwicki,Wojciech Dyszkiewicz,Monika Pasieka-Lis,Dariusz M. Kowalski,Maciej Krzakowski,Jacek Jassem,Janusz Milanowski +25 more
TL;DR: Cytological and small biopsy samples with low content of tumor cells and specimens from metastatic lesions are a sufficient source for EGFR mutation testing in NSCLC patients and the incidence of EGFR gene mutations was similar to those reported in other Caucasian populations.
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