Tomasz Dylag
Jagiellonian University
18 Papers
317 Citations
Tomasz Dylag is an academic researcher from Jagiellonian University. The author has contributed to research in topics: Nociceptin receptor & Neuropeptide FF. The author has an hindex of 12, co-authored 18 publications.
Chat about Author
Papers
Nociceptin inhibits acquisition of amphetamine-induced place preference and sensitization to stereotypy in rats.
Jolanta Kotlinska,Piotr Rafalski,Grazyna Biala,Tomasz Dylag,Krzysztof Rolka,Jerzy Silberring +5 more
TL;DR: The experiments indicated that repeated administration of nociceptin at increasing doses during conditioning significantly attenuated the reinforcing effect of amphetamine in conditioned place preference paradigm, suggesting the involvement of nOCiceptin in long-lasting neuronal adaptation after repeated amphetamine treatment.
66
Synthesis and evaluation of in vivo activity of diphenylhydantoin basic derivatives.
Tomasz Dylag,Małgorzata Zygmunt,Dorota Maciag,Jadwiga Handzlik,Marek Bednarski,Barbara Filipek,Katarzyna Kieć-Kononowicz +6 more
TL;DR: Water-soluble compounds, containing 2-methoxyphenylpiperazine group (11a, 19a), showed strong antiarrhythmic properties in adrenaline-induced arrhythmia; compound 9a {1-[3-(4-(3-chloro-phenyl)-piperazin-1-yl)- 2-hydroxy-propyl]- 3-ethyl-2,4-dioxo-5,5-diphenyl-
58
The activity of CART peptide fragments
Tomasz Dylag,Jolanta Kotlinska,Piotr Rafalski,Agnieszka Pachuta,Jerzy Silberring,Jerzy Silberring +5 more
TL;DR: The activity of CART (85-102) is described, whose ability to exert behavioral responses was confirmed by the observed attenuation of the expression of sensitization to morphine-induced hyperlocomotion and this fragment decreased the number of escape jumps evoked by naloxone in morphine-addicted mice after intracerebroventricular administration.
50
Neuropeptide FF (NPFF) reduces the expression of morphine- but not of ethanol-induced conditioned place preference in rats
TL;DR: The results suggest that NPFF is involved in the expression of morphine reward, and supports an anti-opioid character of this peptide.
48
Rat brain proteome in morphine dependence.
Anna Bierczyńska-Krzysik,Emilia Bonar,Emilia Bonar,Anna Drabik,Marek J. Noga,Piotr Suder,Tomasz Dylag,Adam Dubin,Jolanta Kotlinska,Jerzy Silberring,Jerzy Silberring +10 more
TL;DR: Inspection of protein profiles, following TCA/acetone precipitation and the use of nano-scale liquid chromatography coupled to tandem mass spectrometry allowed for identification of eleven potential dependence markers, mainly cytoplasmic and mitochondrial enzymes, e.g. proteins that belong to GTPase and GST superfamilies.
45