Todd W. Lyons
Boston Children's Hospital
46 Papers
47 Citations
Todd W. Lyons is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Medicine & Meningitis. The author has an hindex of 13, co-authored 36 publications. Previous affiliations of Todd W. Lyons include Harvard University & University of Connecticut.
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Papers
Trends in Capability of Hospitals to Provide Definitive Acute Care for Children: 2008 to 2016.
Kenneth A. Michelson,Joel D. Hudgins,Todd W. Lyons,Michael C. Monuteaux,Richard G. Bachur,Jonathan A. Finkelstein +5 more
TL;DR: It is demonstrated that hospitals are decreasingly providing definitive acute care, with concentration of care in high-volume and pediatric hospitals, and systems improvements are needed to support hospital-based acute care of children.
Validation of a Clinical Prediction Rule to Distinguish Lyme Meningitis From Aseptic Meningitis
Keri A. Cohn,Amy D. Thompson,Samir S. Shah,Samir S. Shah,Samir S. Shah,Elizabeth M. Hines,Todd W. Lyons,Elizabeth J. Welsh,Elizabeth J. Welsh,Lise E. Nigrovic +9 more
TL;DR: Patients classified as low risk by using the Rule of 7′s were unlikely to have Lyme meningitis and could be managed as outpatients while awaiting results of Lyme serology tests.
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Interpretation of Cerebrospinal Fluid White Blood Cell Counts in Young Infants With a Traumatic Lumbar Puncture
Todd W. Lyons,Andrea T. Cruz,Stephen B. Freedman,Mark I. Neuman,Fran Balamuth,Rakesh D. Mistry,Prashant Mahajan,Paul L. Aronson,Joanna Thomson,Christopher M. Pruitt,Samir S. Shah,Lise E. Nigrovic,Dina M. Kulik,Pamela J. Okada,Alesia H. Fleming,Joseph L. Arms,Aris Garro,Neil G. Uspal,Amy D. Thompson,Paul Ishimine,Elizabeth R. Alpern,Kendra L. Grether-Jones,Aaron S. Miller,Jeffrey P. Louie,David Schandower,Sarah Curtis,Suzanne M. Schmidt,Stuart Bradin +27 more
TL;DR: Correcting the cerebrospinal fluid WBC count substantially reduced the number of infants with cerebroSpinal fluid pleocytosis while misclassifying only 1 infant with bacterial meningitis of those aged 29 to 60 days.
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Use of a National Database to Assess Pediatric Emergency Care Across United States Emergency Departments.
Kenneth A. Michelson,Todd W. Lyons,Joel D. Hudgins,Jason A. Levy,Michael C. Monuteaux,Jonathan A. Finkelstein,Richard G. Bachur +6 more
TL;DR: The feasibility of using nationally representative data to assess quality measures for children cared for in the ED is demonstrated and differences between pediatric and general ED care identify targets for quality improvement.
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Disrupted N-linked glycosylation as a disease mechanism in deficiency of ADA2
Pui Y. Lee,Pui Y. Lee,Yuelong Huang,Qing Zhou,Oskar Schnappauf,Michael S. Hershfield,Ying Li,Nancy J. Ganson,Natalia Sampaio Moura,Ottavia M. Delmonte,Scellig S D Stone,Michael J. Rivkin,Sung-Yun Pai,Todd W. Lyons,Robert P. Sundel,Victor W. Hsu,Luigi D. Notarangelo,Ivona Aksentijevich,Peter A. Nigrovic +18 more
TL;DR: A novel pathogenic mutation affecting a consensus N-linked glycosylation sequence is described and the essential role of glyCosylation in the biology of ADA2 is illustrated.
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