Todd Blevins
University of Strasbourg
35 Papers
172 Citations
Todd Blevins is an academic researcher from University of Strasbourg. The author has contributed to research in topics: RNA & RNA silencing. The author has an hindex of 21, co-authored 32 publications. Previous affiliations of Todd Blevins include University of Basel & Indiana University.
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Papers
Four plant Dicers mediate viral small RNA biogenesis and DNA virus induced silencing
Todd Blevins,Rajendran Rajeswaran,Padubidri V. Shivaprasad,Daria Beknazariants,Azeddine Si-Ammour,Hyun Sook Park,Franck Vazquez,Dominique Robertson,Frederick Meins,Thomas Hohn,Thomas Hohn,Mikhail M. Pooggin +11 more
TL;DR: This work highlights the complexity of virus interaction with host silencing pathways and suggests that DCL multiplicity helps mediate plant responses to diverse viral infections.
509
Transgenerational Adaptation of Arabidopsis to Stress Requires DNA Methylation and the Function of Dicer-Like Proteins
Alex Boyko,Todd Blevins,Youli Yao,Andrey Golubov,Andriy Bilichak,Yaroslav Ilnytskyy,Jens Hollander,Frederick Meins,Igor Kovalchuk +8 more
TL;DR: Exposure ofArabidopsis plants to stresses resulted in a higher HRF, increased global genome methylation, and higher tolerance to stress in the untreated progeny, consistent with the hypothesis that stress-induced transgenerational responses in Arabidopsis depend on altered DNA methylation and smRNA silencing pathways.
468
Identification of Pol IV and RDR2-dependent precursors of 24 nt siRNAs guiding de novo DNA methylation in Arabidopsis
Todd Blevins,Todd Blevins,Ram Podicheti,Vibhor Mishra,Michelle Marasco,Jing Wang,Douglas B. Rusch,Haixu Tang,Craig S. Pikaard,Craig S. Pikaard +9 more
TL;DR: The identified Pol IV and RDR2-dependent RNAs (P4R2 RNAs) that accumulate in dcl3 mutants and are diced into 24 nt RNAs by DCL3 in vitro, suggesting a model whereby siRNAs are generated from either end of P4R 2 duplexes by single dicing events.
Evolution of Arabidopsis MIR genes generates novel microRNA classes
TL;DR: The results suggest that evolution of MIR genes is associated with gradual, overlapping changes in DCL usage resulting in specific size classes of miRNAs.
201
Massive production of small RNAs from a non-coding region of Cauliflower mosaic virus in plant defense and viral counter-defense
Todd Blevins,Rajendran Rajeswaran,Michael Aregger,Basanta Kumar Borah,Mikhail Schepetilnikov,Loïc Baerlocher,Laurent Farinelli,Frederick Meins,Thomas Hohn,Mikhail M. Pooggin +9 more
TL;DR: Surprisingly, CaMV titers were not increased in dcl1/2/3/4 quadruple mutants that accumulate only residual amounts of vsRNAs, suggesting this chimeric virus may serve as a decoy diverting the silencing machinery from viral promoter and coding regions.